Developmental abnormalities associated with the hypopigmented retina
für 71.10€ kaufen ··· 9783844310344 ··· 10361113917 ··· The albino visual system is characterised by a range of abnormalities including a severe rod deficit, an underdevelopment of the central retina and a misprojection of a portion of the temporal ganglion cells. During development of the retina levels of proliferation and apoptosis are elevated, and the maturational gradient is delayed. During my PhD I systematically characterised the nature of these developmental abnormalities and examined the effects of L-DOPA (a precursor in melanin/dopamine synthesis pathways that is thought to be depleted in the albino retina) on patterns of cell division. The findings were consistent with a model in which reduced levels of L-DOPA in the albino retina lead to spatiotemporal defects in patterns of cell division, potentially as a result of secondary consequences on concentrations of retinal dopamine. Hersteller: LAP Lambert Academic Publishing Marke: LAP Lambert Academic Publishing EAN: 9783844310344 Kat: Hardcover/Naturwissenschaften, Medizin, Informatik, Technik/Biologie Lieferzeit: Sofort lieferbar Versandkosten: Ab 20¤ Versandkostenfrei in Deutschland Icon: https://www.inforius-bilder.de/bild/?I=E6z%2Bq8NzjTVSiJWENHNp9B6L58tizNp8hAJk5lehkKg%3D Bild:
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