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Genetic Immunization & Cytokine Immunomodulation

für 53.10€ kaufen ··· 9783847312390 ··· 1036199085 ···
In chronic parasitic infections, the interplay between the host and the parasite suggests immuno-suppressive mechanisms developed by the parasite. Echinococcus granulosus, a tiny tapeworm that among other helminthes, favors the induction of T helper type 2 responses which are less severe and less destructive than T helper type 1 responses. This study aimed at exploring the immune response generated in BALB/c mice using genetic immunization technology. Immuno-modulation by the co-delivery of different cytokine genes (IFN- , IL-12, IL-4) was also investigated. Immunization by antigen B or its second subunit (EgAgB8/2) revealed dominated T helper type 2 cytokine response, IgG3 humoral response, low splenocyte cell proliferation, and low CD8+ cell count. However, restored CD8+ cell count, high splenocyte cell proliferation, and high expression of IFN- cytokine in IFN- gene co-immunized mice indicates the efficiency of cytokine gene immuno-modulation in skewing the response toward T helper type 1.
Hersteller: LAP Lambert Academic Publishing
Marke: LAP Lambert Academic Publishing
EAN: 9783847312390
Kat: Hardcover/Ratgeber/Recht, Beruf, Finanzen/Sonstiges
Lieferzeit: Sofort lieferbar
Versandkosten: Ab 20¤ Versandkostenfrei in Deutschland
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5: Ab 20¤ Versandkostenfrei in Deutschland
6: LAP Lambert Academic Publishing
7: Genetic Immunization & Cytokine Immunomodulation
:::: Hardcover/Ratgeber/Recht, Beruf, Finanzen/Sonstiges
···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
···· aufgenommen: 30.07.2020 · 12:19:53
···· & überprüft: 13.11.2020 · 02:56:37
: Genetic : Immunization : Cytokine : Immunomodulation :

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