für 53.10€ kaufen ··· 9783847312390 ··· 1036199085 ··· In chronic parasitic infections, the interplay between the host and the parasite suggests immuno-suppressive mechanisms developed by the parasite. Echinococcus granulosus, a tiny tapeworm that among other helminthes, favors the induction of T helper type 2 responses which are less severe and less destructive than T helper type 1 responses. This study aimed at exploring the immune response generated in BALB/c mice using genetic immunization technology. Immuno-modulation by the co-delivery of different cytokine genes (IFN- , IL-12, IL-4) was also investigated. Immunization by antigen B or its second subunit (EgAgB8/2) revealed dominated T helper type 2 cytokine response, IgG3 humoral response, low splenocyte cell proliferation, and low CD8+ cell count. However, restored CD8+ cell count, high splenocyte cell proliferation, and high expression of IFN- cytokine in IFN- gene co-immunized mice indicates the efficiency of cytokine gene immuno-modulation in skewing the response toward T helper type 1. Hersteller: LAP Lambert Academic Publishing Marke: LAP Lambert Academic Publishing EAN: 9783847312390 Kat: Hardcover/Ratgeber/Recht, Beruf, Finanzen/Sonstiges Lieferzeit: Sofort lieferbar Versandkosten: Ab 20¤ Versandkostenfrei in Deutschland Icon: https://www.inforius-bilder.de/bild/?I=YZADE9dQa9vl%2BWAiJ5tIPKv6LetaFBKxAG%2F7x3IrJDI%3D Bild: