Determination of the Antiretroviral Drug Lamivudine
für 44.10€ kaufen ··· 9783846528778 ··· 1036187199 ··· A solid-state iodide selective electrode with Ag2S-AgI adsorbed on graphite rod, recovered from a dry cell, was prepared and validated for its typical response characteristics with an objective to develop a potentiometric titration system for rapid measurements of Lamuvidine (LMV) in tablets used as an antiretroviral drug for Hepatis B and HIV patients. The partial validationexhibited typical response values of linear range of 10-6 to 10-1 M iodide and a slope 57.57 mV/decade which reasonably agreed with early data from our Laboratory.The basis of LMV determination is its oxidation by excess bromine generated from bromate-bromide mixture. The unreacted bromine oxidized the added excess iodide to iodine. The amount of bromine consumed by LMV, the basis of its determination, was determined by subtracting the back-titrated iodine with thiosulphate whose end-point was located potentiometrically with the solid state iodide selective electrode against a reference electrode. The iodometric back titration provided for the indirect determination of 1-30 mg LMV in turbid tablet test solutions. Hersteller: LAP Lambert Academic Publishing Marke: LAP Lambert Academic Publishing EAN: 9783846528778 Kat: Hardcover/Ratgeber/Recht, Beruf, Finanzen/Ausbildung, Beruf, Karriere Lieferzeit: Sofort lieferbar Versandkosten: Ab 20¤ Versandkostenfrei in Deutschland Icon: https://www.inforius-bilder.de/bild/?I=4FT1O14eVUb%2FuUW%2BouS2IxUjYgWDozM549x%2BPfIJojY%3D Bild:
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