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HIV Genetics Evaluation And Viral Dynamics

für 44.10€ kaufen ··· 9783846555415 ··· 1036189062 ···
There are the two type of HIV mainly they are HIV-1 and HIV-2. HIV-2 is less pathogenic and less transmissible compared to HIV-1. This is believed to be due to the lower viral load that is seen in HIV-2 infected patients. genetic variation and evolution in the pol gene was studied, with special interests in resistance-associated mutations in HIV-2 infected patients failing antiretroviral treatment. There is observation in some mutations known to cause resistance in HIV-1 such as M184V, Q151M and E219D but most resistance mutations appeared to differ from what is known in HIV-1. The main conclusion from this work is that specific algorithms for HIV-2 resistance interpretation are needed, because the algorithms for HIV-1 cannot be used. They were studied the evolution of co-receptor usage, neutralization escape and env gene sequence. It is reported that a switch from CCR5 to CXCR4 using virus during disease progression. They did not see a clear pattern of neutralization escape as is seen in HIV-1. A pattern of changes in the number of potential N-linked glycosylation sites during disease progression has been observed. HIV-2 has fewer potential N-linked glycosylation sites in V3.
Hersteller: LAP Lambert Academic Publishing
Marke: LAP Lambert Academic Publishing
EAN: 9783846555415
Kat: Hardcover/Naturwissenschaften, Medizin, Informatik, Technik/Medizin/Pharmazie
Lieferzeit: Sofort lieferbar
Versandkosten: Ab 20¤ Versandkostenfrei in Deutschland
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5: Ab 20¤ Versandkostenfrei in Deutschland
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7: HIV Genetics Evaluation And Viral Dynamics
:::: Hardcover/Naturwissenschaften, Medizin, Informatik, Technik/Medizin/Pharmazie
···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
···· aufgenommen: 30.07.2020 · 11:13:55
···· & überprüft: 13.11.2020 · 02:11:39
: Genetics : Evaluation : Dynamics :

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