Heterocycles in Organic Synthesis: Their Synthesis and Applications
für 71.10€ kaufen ··· 9783843378444 ··· 10361101534 ··· Based on the recorded pharmacological potencies of numerous substituted pyrimidines as antihyperlipemic and antihypertensive agents, synthesis of condensed and spiro bis-heterocyclic systems oxazole-pyrimidines as well as pyrimido-oxazines bearing a phosphonate substituent was undertaken. The bioassay indicated that some of the products have effect on the central nervous system (CNS), and other products have good selective anti-tumor activity and the structure-activity relationship (SAR) of new phosphonates has also been indicated. In addition, a new class of C-glycosyl amino acids bearing a thiourea segment as a linker has been designed and synthesized by addition of glycosylmethyl isothiocyanates to an amine-functionalized amino acid. The orthogonal set of protective groups makes these compounds suitable substrates for the co-translational modification of natural peptides. The study included the synthesis of a set of new sugar isothiocyanates and their coupling with the alanine derivative. Hersteller: LAP Lambert Academic Publishing Marke: LAP Lambert Academic Publishing EAN: 9783843378444 Kat: Hardcover/Naturwissenschaften, Medizin, Informatik, Technik/Chemie Lieferzeit: Sofort lieferbar Versandkosten: Ab 20¤ Versandkostenfrei in Deutschland Icon: https://www.inforius-bilder.de/bild/?I=XC%2FfhSk68GeCaa4JyCf4N1b3QMMfFCVTaC4HMrFoWo4%3D Bild:
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