für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray La terapia fotodinámica (TFD) es un nuevo y prometedor tratamiento de cáncer que emplea la combinación de un fotosensibilizador y la luz visible en presencia de oxígeno. En TFD, la luz visible activa a una droga fotosensibilizadora y produce oxígeno singlete, así también como otras especies reactivas del oxígeno (ROS) que inducen muerte celular y regresión tumoral. Esta terapia gatilla una serie de procesos fotoquímicos y fotobiológicos los cuales resultan involucrados en múltiples vías durante la muerte celular. En este trabajo se estudió el efecto de diferentes metaloporfirinas (TMP, CuTMP, ZnTMP y CdTMP) y metaloftalocianinas (ZnPcOCH3, ZnPcCF3 y ZnPcPC). En estudios in vitro , ZnPcOCH3, en condiciones de oscuridad no provoca cambios en la supervivencia e induce una pronunciada disminución de la viabilidad celular dependiente de la dosis de luz. Por otra parte los resultados de ZnPcOCH3-TFD mostraron que las células y las mitocondrias fueron modificadas ultraestructuralmente y los lisosomas dañados parcialmente. Este tratamiento ` in vivo` produce regresión tumoral del 50, 70 y 100% dependiendo de la dosis de irradiación, encontrándose involucrado el proceso apoptótico. ····· 10361136904
für 26.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Los diversos escenarios dibujados por el cine, la televisión, la radio y el internet, sugieren que de la ciencia puede esperarse `todo , menos entenderla. Cambiar esta visión es uno de los propósitos fundamentales de las actividades de divulgación de la ciencia. El presente trabajo ofrece la descripción detallada de una propuesta museográfica que explora la conexión entre tres conceptos: evolución, adaptación y biodiversidad, a través de diversos recursos museográficos relacionados con lo que los ojos (propios y ajenos) pueden ver. La propuesta se encuentra dividida en dos partes: la primera corresponde al marco teórico que brinda un panorama general acerca de las estrategias y los propósitos de los museos de ciencias, así como las bases científicas y didácticas sobre las que descansa la propuesta. La segunda parte corresponde propiamente a la presentación de la propuesta museográfica e incluye las fichas museográficas de tres unidades museográficas que, en conjunto, ofrecen una visión holista sobre la diversidad genética al interior de una especie, la diversidad de especies (y adaptaciones), y las diversas relaciones que pueden establecerse entre ellas y su ambiente. ····· 10361136898
für 35.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray La administración de los recursos pesqueros, requiere de conocimientos biológicos básicos para hacer más dinámico el flujo de producción y mercado a lo largo del tiempo. Por ello, se condujo la presente investigación destinada a aportar conocimientos sobre aspectos reproductivos del pejerrey Odontesthes regia regia que sirvan de base para mejorar su manejo pesquero. Se procesaron y analizaron histológicamente 1590 ovarios, con cuyos resultados se describió el ciclo reproductivo y se obtuvieron los valores de las tallas de primera madurez gonadal y de fecundidad. Se calculó la talla media y de primera madurez en 15 y 14 cm de longitud total, respectivamente. La fecundidad parcial fue estimada en 1 174 ovocitos por tanda de desove y la fecundidad relativa en 56 ovocitos por gramo de peso en los periodos de mayor actividad reproductiva de los años 1996 y 2003 ····· 10361136767
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Los humedales artificiales son considerados como procesos físico-biológicos aplicados en la depuración de agua residual y dentro de las alternativas que existen al respecto, son los que menos gastos de operación requieren. Implementarlos, demanda el desarrollo de conocimientos básicos entre estos están: determinar el listado de las plantas acuáticas nativas con potencial para ser usadas, conocer los materiales propios de la región que pueden ser aprovechados como soportes y sus efectos en la depuración y por último hay que establecer la hidráulica que debe ser usada en los sistemas. Este trabajo muestra el listado de plantas acuáticas de la región de Durango, Dgo. y su relación con calidad del agua además de establecer el papel que juegan tres de las especies y el soporte utilizado en la remoción de fosfatos solubles, amoniaco y coliformes fecales de agua residual doméstica, en micro-humedales sub-superficiales. ····· 10361136763
für 62.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray El Golfo de México sustenta al ostión Crassostrea virginica como recurso alimenticio, pero en algunos sitios las concentraciones de metales tóxicos han aumentado. Bioensayos con Cr y Cd en ostión nativo de costas mexicanas permitieron asociar los efectos con la acumulación de los metales. Los biomarcadores de exposición (metalotioneínas) y efecto (lipoperoxidación), y los modelos fisiológicos analizados permiten proponer a C. virginica como acumulador neto de Cd, pero no de Cr. El gasto metabólico para compensar la toxicidad del Cr podría afectar su crecimiento pero, aunque se adaptan, pueden incorporar concentraciones consideradas peligrosas para el hombre. En contraste, la toxicidad del Cd impide al organismo adaptarse, ingresando rápidamente a una zona de resistencia metabólica y acumulando altas concentraciones del metal. Los niveles de Cd registrados actualmente en el sitio de origen de los organismos podrían representar riesgo. El conocimiento de la tolerancia de las poblaciones nativas de ostión y las normas de control de la contaminación pueden complementarse para proteger al recurso. ····· 10361136506
für 35.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Un estudio de los sistemas de producción animal localizados en las delegaciones y municipios conurbados de la Ciudad de México, fue llevado a cabo para conocer sus características sociales, culturales y tecnológicas. El análisis incluyó una propuesta metodológica de Agenda 21 que integró la aplicación de variables derivadas de las dimensiones económicas y sociales y las políticas internacionales que pueden auxiliar para el desarrollo sostenible de países en desarrollo las estrategias de combate a la pobreza y la miseria los cambios que son necesarios introducir en los patrones de consumo la mejora de calidad de vida y asentamientos humanos, la conservación y la cuestión de los recursos para la protección de la atmósfera y viabilización de la transición energética y, finalmente, la prioridad que se debe dar a la gestión, a la manipulación y a la disposición ambientalmente racional de los residuos sólidos. ····· 10361136255
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Los modelos del cambio climático sugieren un incremento de concentraciones de CO2 y cambios en las pautas de llegada de las precipitaciones, lo que se traduce en incrementos en los extremos climáticos generales. El CO2 es una variable clave que afecta al desarrollo y función de las plantas, dado que es esencial para realizar la fotosíntesis por lo que dichos incrementos derivados del cambio climático afectarán al crecimiento de los cultivos. Muchas de las respuestas fisiológicas observadas frente al aumento del CO2 atmosférico están influenciadas por su interacción con otros estreses, como por ejemplo la salinidad, debido al creciente aumento de las áreas afectadas por la salinidad y su impacto sobre la masa vegetal. Por ello, en este libro, se expone como la agricultura desarrolla una función muy importante en la lucha contra el cambio climático debido a su papel como secuestradores de CO2 atmosférico. Las conclusiones de este trabajo ayudarán a clarificar aspectos esenciales para elegir las soluciones más efectivas en este ámbito junto con otras problemáticas dadas en nuestras tierras de cultivos como son el estrés salino, el cual se verá implementado por dicho cambio climático. ····· 10361136205
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Se le sugiere, que ante la gran incertidumbre y falta de datos representativos del comportamiento invasor de algunas plagas en nuestra área cercana, como forma de prevenirlas trate de anticiparse al riesgo y disminuir sus vulnerabilidades participativamente. Un resumen elemental que ha sido realizado con fines de bioseguridad y vigilancia para los países caribeños. Damos los datos de nuestra experiencia en vigilancia durante 30 años. Se le invita a que se preocupe y ocupe del peligro que representan las plagas para nuestros países con un resumen de lo más importante. La brújula ante la falta de conocimiento, puede estar en la lista de cuarentena de los gobiernos de la región e inventarios nacionales que periódicamente deben publicarse, tanto para áreas naturales como cultivadas. Si a usted la interesa la problemática, de la bioseguridad, el desarrollo sostenible, el medio ambiente, o porque es docente, o productor, o es un ciudadano común consciente y comprometido con la creación que necesita saber, entonces usted va a encontrar en este libro a la horma de su zapato. Le prometo que aunque tenga fácil acceso a la WEB, le va a ser de utilidad. Un abrazo del autor. ····· 10361136080
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Population genetic structure is widespread in many organisms and can be found at small spatial scales. Population genetic differentiation is an evolutionary precursor to speciation and can have a significant impact on the microevolutionary dynamics of a region. Levels of divergence, in turn, are determined by numerous ecological and evolutionary factors operating on multiple spatial and temporal scales, including spatial heterogeneity, population size and dispersal. My dissertation uses microsatellite markers to investigate the population genetic structure of three vertebrate species that coexist on a common landscape and share ecological predator-prey and competition interactions. I then identify ecological and evolutionary processes important in shaping the observed patterns within a comparative framework. Finally, I explore evolutionary processes that shape adaptive divergence in one of the species, by comparing levels of population differentiation at quantitative traits and neutral molecular markers among ecotypes. ····· 10361136047
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This book is the story of the search to discover the biological basis of seed behavior in the weedy Setaria species-group. It consists of seven chapters, five experimental, a concluding essay and an introduction. The first two are from studies by Milt Haar. In the first, stable and plastic seed productivity behaviors are studied in terms of plant architecture. In the second, the structure of seed dormancy (seed heteroblasty) is elucidated. In the next three by Kari Jovaag (based on field experimental work by Brad Atchison), seed heteroblasty defines the evolutionary ecological role this complex functional trait plays in determining seedling emergence. In the third article seed heteroblasty in several populations is defined. In the fourth article, the role seed heteroblasty plays in the annual cycling of germinability-dormancy in soil seed pools is described. In the final of this series, seedling emergence (pattern and magnitude) of the populations studied is presented. The conclusion of this work is that the number and quality of the seed produced during embryogenesis is the predicate, the blueprint, for seedling recruitment timing and extent. ····· 10361135985
····· lezzter Preis 71.10€ ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Ultraviolet Radiation (UV) has been shown to suppress immunological parameters in both animal models and humans. It has been postulated that this UV induced immune suppression may lead to an increase in susceptibility to infectious diseases and allow the outgrowth of transformed tumours leading to the development of skin cancer. The aim of the research presented in this book was to further understand the mechanisms of UV induced immune suppression in both mice and humans. The research focuses on the role of urocanic acid, cytokines, and wavelength interactions and examines their involvement in UV mediated immune suppression. This book is essentially the publication of a PhD thesis and would appeal to research scientists, clinicians and students working in the field of photoimmunology or skin biology. ····· 10361135745
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Our work is a contribution towards understanding the biology of mobile genetic elements (MGE). These constitute a significant proportion of most eukaryotic genomes. We demonstrate the presence of signals at the sites where mobile genetic elements preferentially insert in several genomes. These signals have been mapped into a general machine learning protocol. A web enabled computational protocol for the analysis of mobile genetic elements and their insertion sites, and a resource base containing several genomes,termed ELAN has been developed. This suite of tools for analysis and a relational database which contains over several hundred gigabytes of information are in the public domain. MGE insert strategically, selecting their sites carefully without disrupting exonic regions in the human genome but insert multiple copies in intronic as well as intergenic regions. More details can be found at nldsps.jnu.ac.in/elan.html ····· 10361135723
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray A study was conducted for 21 days of pre-composting and 49 days of vermicomposting under laboratory condition by using earthworm (Lumbricus rubellus). Three different combination of treatments were prepared with eight replicates for each treatment, namely cow dung : kitchen waste in 30:70 ratio (T1), cow dung : coffee grounds in 30:70 ratio (T2), and cow dung : kitchen waste : coffee grounds in 30:35:35 ratio (T3) were used for this study. By comparing the numbers and weights of earthworms in each treatment, only T2 indicated significant difference (p 0.05) which it can be concluded that coffee grounds influenced the development of earthworms population. Nutrient elements in the vermicompost from each treatment were measured and relatively showed high percentage in C, N, P, K, Ca, and Na. Contrast for Mg and other micronutrient elements, the result showed small percentage in Zn, Cu, Fe, Mn, B, and crude fat. The data reveals that coffee grounds can be decomposed through vermicomposting by using Lumbricus rubellus into value-added material. With the correct ratio and suitable condition of kitchen waste, coffee grounds can also be used as stabilizer in vermicomposting. ····· 10361135713
····· lezzter Preis 61.20€ ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Anthropologists earlier believed the tree shrew (Tupaia belangeri) to be a close relative of primates and classified the species in the prosimian suborder. Although that classification has now been questioned, the tree shrew undoubtedly represents a pivotal chapter in the natural history of the evolution of the brain. With its cone dominated retina, this animal is capable of carrying out color discrimination under isoluminant conditions (i.e. where hue alone is the cue). Unlike primates, it is capable of doing so even after ablation of the primary visual cortex. This book purports to be an electrophysiological examination of the functional architecture and integrative circuitry required for color vision in both the visual cortex and subcortical structures. It is, thus, a contribution to the study of the evolution of color vision -a topic which not only concerns Psychologists but is increasingly the focus of much attention among Philosophers. ····· 10361135669
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Aquatic biodiversity includes all organisms living in fresh water reservoir. These aquatic organisms contribute to (1) food (2) medicine and other use for mankind. Use of fish and growing of fish and fishing is a common practice everywhere. The benefits of the development of aquatic biodiversity are: (i) Food production-particularly of animal protein obtained for common people (ii) Providing new employment opportunity to rural people thereby checking migration of people (iii) Improving economic condition of rural people in particular through integrated project (iv) Utilization of waste food and organic wastes for food production. Keeping in view the importance of aquatic organisms in shaping the nation`s economy the present volume intends to highlight some important aspects of aquatic biodiversity. This textbook focuses on different organisms studied by the authors. The contents have been organized in `self-contained` units for ease of understanding. The initial chapters deal with fundamental aspects of reservoir and hydrochemistry. The organisms are then analyzed, with emphasis on the important characters and systems of classification for each category of organisms. ····· 10361134584
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Soumen Bhattacharjee did his masters in Zoology from Calcutta University and doctoral thesis in Indian Institute of Chemical Biology, Calcutta, under Jadavpur University, India. His experience with human polyomaviruses continued from 1996. His doctoral work involved genotyping and promoter-enhancer analysis of endemic BK polyomavirus amplified directly from human patient body fluids in eastern India. He has published in reputed journals from all over the world. Presently he is involved in detection and genomic characterization of BKV, JCV, KIPyV, WUPyV and MCPyV in the northern part of West Bengal, India. ····· 10361134554
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Denitrification is an important process that helps to reduce soil sediments of nitrate. In a wetland environment denitrification process is a valuable process that helps to reduce nutrients build up that may result in algae bloom and with consequential ecosystem problems. The research The effect of heavy metals on denitrification in wetland sediment aimed at looking at how sediments with various load of heavy metals contaminants could affect the efficiency of denitrification process. The investigation was carried in the laboratory using sediments sampled from the constructed wetland in Linkoping, which receive effluents from sewage treatment plant. Wetland has a unique relevance both as a habitat for many species of plants and animals,but also a place for numerous biochemical processes.I am delighted to present you some of the findings and discussions. The book has element of environmental chemistry and will invaluable for teaching and learning in environmental science for colleges.I am highly grateful to the staff members of Water and Environmental Studies, Linkoping University, particularly Prof Bo Svensson for the supervision and suggestion. ····· 10361134536
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The thermostable properties of the Taq DNA Polymerase from Thermus aquaticus have contributed greatly to yield, specificity, automation and utility in the PCR for amplification of DNA. Isolation of this protein from T. aquaticus is difficult. Several studies have shown the recombinant expression of Taq DNA Polymerase in heterologous host cells. However, these still suffer from low yields. The use of T7 RNA Polymerase regulated expression vector and availability of affinity tag (His Tag) can make the expression of Taq DNA Polymerase an efficient and economical process. The project is aimed in recombinant expression of Taq DNA Polymerase in BL21 host cell line and pET expression vector. ····· 10361134521
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Aspergillus nidulans grows on a myriad of substrates gene expression is highly regulated to adapt to changes in substrates. AcuK and AcuM transcription factors have been discovered to be involved in the regulation of gluconeogenesis. Research into the expression of genes under AcuK/AcuM control could provide answers to regulatory mechanisms in higher eukaryotes such as humans. Findings from studies on A. nidulans can assist in drug (antifungal) development. This book gives insight into carbon metabolism in A. nidulans and AcuK/AcuM regulation of the expression of selected genes that possess the putative CCGN7CCG sequence in their promoter regions. It explores the conservation of CCGN7CCG in maeA, acuF and alxA (which encode NADP-dependent malic enzyme, phosphoenolpyruvate carboxykinase and alternative oxidase) of other Aspergilli and how these genes are regulated under ethanol induced conditions. The book explains how semi-quantitative RT-PCR analysis can be used to evaluate mRNA levels between acuK248 and acuM301 mutants and the wild type. This book will benefit researchers and students in the field of biochemistry and molecular biology of filamentous fungi. ····· 10361134513
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The technical research entitled `Assessment of Floral and Faunal Diversity of Prok and Chumchet VDC in Manaslu Conservation Area` deeds to explore the current status of major floral and faunal diversity, identification of hotspots of major species and establishment of permanent transect lines for biodiversity monitoring and survey. GPS was used to record the position of each sampled plots and observed specimens. Reconnaissance survey and direct observation/measurement was carried out to gather primary data about floral and faunal diversity. Both Direct observation through different transects and indirect evidences through interview and literature survey was carried to enlist mammal, reptile and bird species. The sample plots were laid out randomly with the sampling intensity 1% for trees, 0.5% for shrubs and 0.001% for herbs. The collected data were analyzed by using Arc-view and MS-Excel 2003 software and demonstrated through maps and tables. ····· 10361134498
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This book provides potential novel targets for therapies of human cancer and inflammatory diseases. The studies in this book have revealed the cryptic activity within the FnIII-1 module modulates the tissue inflammatory response and suggests that fibronectin (Fn) matrix remodeling can induce the expression of cytokines by stromal cells present in the tissue microenvironment, providing evidence for a previously unrecognized link between fibronectin matrix remodeling and the regulation of the innate immune system. These studies have dissected FnIII-1c`s effects on fibronectin matrix from its effects on the activation of intracellular signaling, elucidated the mechanism by which unfolding of fibronectin Type III-1 domain regulates inflammatory response in tissue microenvironment and clarified how local mechanical properties within tissue microenvironment may protect tumor cells from therapeutic treatment. ····· 10361134399
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Common Vetch, Cow pea, Faba bean,Lentil and Pea cultivars were included in this book. Field and laboratory investigations were related to seed germination performance of varying cultivars under matric potential water stress using filter papers (no ion attraction),varying osmotic created by dissolving sodium chloride (Ion attraction), and in soil (combination of osmotic and matric potentials). Field trails were conducted to study the role water stress Irrigation, supplementary irrigation, rainfall incidences on growth, flowering and yield besides the anatomical alterations that can be caused by the above mentioned parameters. Furthermore, growth regulators and micro nutrients were applied to find out the possibilities of these materials in mitigating the adverse effects of water scarcities on rooting, growth, flowering and yield.Finally,all used cultivars were categorized according to their relation to drought, as some were drought escape,conservatives, semi-conservatives. ····· 10361134188
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Electrical remodeling is a persistent change in the electrophysiological properties of myocardium in response to a change in rate or activation sequence. Although it is well established that alterations in heart rate or activation sequence induce electrical remodeling in atria, heart rate and activation sequence-induced electrical remodeling in ventricle are poorly understood. This research shows that persistent changes in ventricular repolarization can be induced by surprisingly short periods of altered rate or activation sequence, and the nature of ventricular electrical remodeling induced by these two protocols is different. This research suggests a novel mechanism for triggering electrical remodeling in ventricle. ····· 10361134187
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Reticulocytosis is an important previously unappreciated surrogate marker of recent Plasmodium falciparum reticulocyte parasitation. Evidence from studies in murine and primate models show increased prevalence of Plasmodium falciparum parasitisation of reticulocytes. The increase in reticulocyte infection has been attributed to compensatory reticulocytosis and increased parasite densities. However, the prevalence of P. falciparum parasitisation of reticulocytes in human populations in holoendemic areas of malaria is unknown. Therefore, the current study examined the prevalence of P. falciparum parasitation of reticulocytes and its association with clinical, parasitological and haematological outcomes in children and adults with acute P. falciparum malaria and healthy malaria -ve controls from a holoendemic area of malaria of western Kenya.Results of this study demonstrate higher prevalence of reticulocyte parasitation in children. Thus, it seems likely that P. falciparum reticulocyte parasitation leads to a burst in compensatory reticulocytosis in acute paediatric malaria predictable by HDP and a febrile illness among children ····· 10361134089· 1 · ::::: · 3 ·· 4 ·· 5 ·· 6 ·· 7 ·· 8 ·· 9 · ::::: · 36 ·
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