für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Electrical remodeling is a persistent change in the electrophysiological properties of myocardium in response to a change in rate or activation sequence. Although it is well established that alterations in heart rate or activation sequence induce electrical remodeling in atria, heart rate and activation sequence-induced electrical remodeling in ventricle are poorly understood. This research shows that persistent changes in ventricular repolarization can be induced by surprisingly short periods of altered rate or activation sequence, and the nature of ventricular electrical remodeling induced by these two protocols is different. This research suggests a novel mechanism for triggering electrical remodeling in ventricle. ····· 10361134187
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Reticulocytosis is an important previously unappreciated surrogate marker of recent Plasmodium falciparum reticulocyte parasitation. Evidence from studies in murine and primate models show increased prevalence of Plasmodium falciparum parasitisation of reticulocytes. The increase in reticulocyte infection has been attributed to compensatory reticulocytosis and increased parasite densities. However, the prevalence of P. falciparum parasitisation of reticulocytes in human populations in holoendemic areas of malaria is unknown. Therefore, the current study examined the prevalence of P. falciparum parasitation of reticulocytes and its association with clinical, parasitological and haematological outcomes in children and adults with acute P. falciparum malaria and healthy malaria -ve controls from a holoendemic area of malaria of western Kenya.Results of this study demonstrate higher prevalence of reticulocyte parasitation in children. Thus, it seems likely that P. falciparum reticulocyte parasitation leads to a burst in compensatory reticulocytosis in acute paediatric malaria predictable by HDP and a febrile illness among children ····· 10361134089
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Chondrocytes live isolated in the voluminous extracellular matrix of cartilage, which they secrete and is neither vascularized nor innervated. Nutrient and waste exchanges occur through diffusion leading to low oxygen tension around the cells. Consequently even normal cartilage under normal physiological conditions suffers from a poor reparative potential that predisposes to degenerative conditions, such as osteoarthritis of the joints, with significant clinical effects. One of the key challenges in medicine is the structural and functional replacement of lost or damaged tissues. Current therapeutical approaches are to transplant cells, implant bioartificial tissues, and chemically induce regeneration at the site of the injury. None of them reproduces well the biological and biomechanical properties of hyaline cartilage. This thesis investigates the re-differentiation of chondrocytes and the repair of cartilage mediated by signaling molecules, biomaterials, and factors provided in mixed cellular cultures (co-culture systems). ····· 10361134077
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Fodder beet(Beta vulgaris),a member of Chenopodiaceae,is a higher productive forage crop,used in farm animals.it is succulent,palatable,digestble and is of high nutritional value(12 M J/Kg D M,NFE =72% DM).It is not common in the Sudan and there is no scientific research concerning its production.Thus an experiment to evaluate the performance of three beet cultivars for their growth,yield,quality under 0.0,40,80,120 Kg N/ha and 15,20,25 plant spacing,was carried out at the Demonstration farm-College of Agricultural Studies (Shambat)-Sudan University of Science and Technology(2007-2009).The feeding value of beet(feed intake,milk yield and composition)compared to fodder sorghum(CV Abu70),the existing popular grass forage,was carried at the Milk Farm-Animal Production College-Sudan University.80 Kg N/ha and 15cm result in better growth,higher yield(60 Green,7 Dry t/ha) and good quality.The nutritive, feeding value of beet is better than Abu70 ,it reduced cost of feeding by 30%and increased profits.So beet proved its success in sub-tropical areas as a winter fodder crop.This work is useful for researchers,postgraduates in plant and Animal production and for meat and milk producers. ····· 10361133956
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The brain cells called neurons are meant to divide rapidly. Brain cancer starts in just one cell when a division starts dividing in an uncontrolled manner. As the cell makes more copies of itself, it grows to form a tumor, may be Benign or Malignant tumors. Immunohistochemical study of tissue Transglutaminase (tTG) in 22 brain tumor samples was performed. tTG expression was observed visually in endothelial and tumor cells. In most of the cases, the tTG expression was observed in endothelial cells but in few cases tTG expression was also observed in tumor cells along with endothelial cells. This shows that tumors were of high grade. We observed benign and malignant tumours like Meningioma, Papilloma, Adenoma, Astrocytoma, Glioblastoma, Multiforme Glioblastoma, Gemistocytic and Neurocytoma. Twelve females and ten males were among patients having age ranged from 8-61yrs.. The tumor were graded according to WHO grading system from grade one to grade four .Low grade tumors were more in comparison to high grade tumors. The tissue Transglutaminase expression was expressed in terms of percentage where high grade tumors showed higher percentage of expression compared to low grade ones. ····· 10361133948
für 55.71€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Adolescence is a critical period of the lifespan, characterised by major physical, chemical and emotional changes. The need for a nutritionally adequate diet is of paramount importance to ensure optimum growth and development. Eating behaviours that are learned early in life are maintained in adulthood. Nutritional inadequacies influence not only adolescents` health but also risk for major chronic diseases in adulthood. As teens become more independent, they make more of their own food choices. Factors that adolescents viewed as influencing their food choices include hunger, appeal of food, time considerations of adolescents and parents, convenience of food, food availability, parental influence on eating behaviours, benefits of foods, situation-specific factors, mood, body image, habit, cost, media and vegetarian lifestyle. The present book has reviewed comprehensively key features of adolescent eating patterns which includes meal skipping, snacking, fast food consumption, inadequate intake of fruits, vegetables, and dairy and other calcium-rich foods, and unconventional dietary patterns such as adopting specific weight loss diet. ····· 10361133901
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The present investigation entitled Physiological characterization of rice germplasm for drought tolerance and yield regulating mechanism under different water regimes was conducted at Instructional farm of I.G.A.U, Raipur during kharif season of 2006 with twenty germplasm lines. The experiment was also carried out in net house (control condition) and rain out shelter to protect the drought plots from rain and also for getting the samples for biochemical analysis. Germplasm is a valuable source of base population and provides the material for breeding. The nature and magnitude of divergence would help the plant breeder in choosing the right type of parents for broad spectrum of variability. ····· 10361133780
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray I used OPN-/- mice to evaluate osteopontin s involvement in immune organ homeostasis in response to physical stress. Using the hindlimb unloading model, I compared OPN-/- mice with OPN+/+ mice subjected to HU for 3 days. Whereas OPN+/+ mice suffered a marked reduction of body weight and significant spleen and thymus atrophy, OPN-/- mice were much less affected. OPN deficiency seemed to protect mice from reduction of lymphocytes in the spleen and thymus, elevation of the level of corticosteroid and apoptotic cell death. In another stress model, chronic restraint stress, I showed that OPN-/- mice are more resistant, compared to OPN+/+ mice, to CRS-induced lymphoid organ atrophy and unable to increase corticosterone production in response to CRS. ACTH also did not respond to stress in the absence of OPN. Administration of OPN into OPN-/- mice or of the anti-OPN monoclonal antibody 2C5 into OPN+/+ mice partially restored the WT and KO phenotypes respectively. Taken together, these results indicate that OPN is critical in mediating stress-induced immune organ atrophy, likely through influencing hypothalamus-pituitary-adrenal axis hormone responses. ····· 10361133708
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray In the present investigation,the efficacy Allyl isothiocyanate(AITC)against N-nitrosodiethylamine induced experimental liver carcinogenesis and in human hepatoma cell line (HepG2)were studied.Cell migration inhibition effect of AITC reveal that the drug has a role in delay of cancer progression . The dose dependent protein expression of P53 and Caspase 3 disclose the anticancer potency of the drug AITC.This was confirmed by various biochemical,molecular biological and histopathological examinations as well. ····· 10361133685
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray In today`s present, the trend is to use fungicide for the control of fungi, which is harmful for the human consumption. The development of pest resistance and problems of environmental pollution have accompanied excessive reliance on pesticides. These problems can be avoided or minimized by using the natural material products such as medicinal plant extracts.The present studies indicated that Allium sativum extract was able to inhibit the growth of two bacteria (Escherichia coli and Staphylococcus aureus) and two fungi (Aspergillus niger and Alternaria solani) studied. ····· 10361133657
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Oral cancer is believed to progress through sequential stages of premalignancies to invasive cancer. Once cancer is formed, the prognosis is poor. The 5-year survival rate of less than 50% is one of the worst among major human cancers. One of the essential keys to improving this gloomy prognosis lies in early diagnosis and proper management of premalignant lesions. A central dogma of carcinogenesis is that alteration to critical control genes underlies malignant transformation. A major focus of this thesis was to study early molecular pathways of oral cancer development. We use Loss of Heterozygosity (LOH), a molecular analysis that can detect the phenotypic change of genome and can work on minute archival material. This thesis has not only provided a comprehensive overview of oral cancer and premalignant lesions with description on their etiological factors and clinicopathological features, but also provided data to establish molecular progression models for oral cancers, and has yielded the first evidence that premalignancies with different molecular risks could be managed differently. The results not only provide insight into the mechanism of early cancer development. ····· 10361133543
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Co-enzyme A (CoASH) and carnitine fulfil several vital roles in the catabolism of both fat and carbohydrate within skeletal muscle. During exercise when the competition between the two metabolic pathways for the involvement of CoASH and carnitine is increased, their relative availability may play major roles in skeletal muscle fuel selection. However, the direct roles of CoASH and carnitine in muscle fuel selection during exercise have not been closely investigated in humans. This publication documents the first attempts to increase muscle CoASH content in humans, and the first demonstration that human muscle carnitine content can be increased by dietary means. Furthermore, the latter was shown to have a profound influence upon muscle fuel metabolism during exercise and exercise performance. Thus, the present data, submitted as a PhD thesis, adds valuable knowledge to our understanding of the regulation of muscle fuel metabolism during exercise in healthy humans. The findings will likely have important implications to both athletic performance as well as certain disease states where muscle metabolism is perturbed. ····· 10361133456
····· lezzter Preis 44.10€ ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray As we face global population growth, increased competition for land and water resources from industrial and urban growth, climate change and the need to protect the environment, we need new solutions to increasing agricultural productivity to combat hunger and poverty. One particularly effective form of bioconversion biotechnology is mushroom cultivation for food, and also for the production of mushroom derived substances. Mushroom production is so far the most profitable way of utilizing ligno-cellulose containing waste materials into foods of higher yields, protein and gross energy per unit area of land. This book investigates the effect of compost size/height, composting period and supplementation on the yield of mushrooms. Mushrooms are gaining popularity due to its nutritive, medicinal and spiritual uses. ····· 10361133253
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Culturing of plant tissues and its ability to proliferate has enabled to increase the knowledge in many science areas including differentiation, tissue division, nutrition and transformation. In most instances, efforts have been directed towards providing aseptic conditions rather than getting into deep-dive science components associated with the type of contaminants, physiological status of inhabitant plant tissue, growing and growth conditions etc. The area of tissue culture has been progressed as an art rather than science which necessitates exploring the elements of scientific intricacies with much needed clarity for rendering solutions to complex problems. The present review highlights the importance of science component at different growth stages in the whole gamete of this most widely practiced plant technique which otherwise sparsely dealt in the past. Furthermore, an attempt has also been made to enlist the challenges linked in developing haploid & DH plants and possible ways to address them from research experiences of our own and from others. ····· 10361133168
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray DHF (dengue hemorrhagic fever), is one of the acute infectious diseases to public health problems who live tropical areas, including in Indonesia. The spread of the disease caused by mosquito vectors. One of these a Aedes aegypti mosquito. Many ways have been done to eradicate mosquitoes, both chemical and biological. Aceh is one of the largest patchouli (Pogostemon cablin Benth.) oil producers in Indonesia (about 90%). So a lot of distillates waste of patchouli. therefore the idea to make biological larvacide by utilizing patchouli leaf dregs. described in this book about how to manufacture leaf dregs Pogostemon cablin Benth extract and treatment procedures as a larvacide. It is hoped this book can help students and researchers who wanted to do research on biological larvacide. ····· 10361133162
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This book is a comprehensive approach to all of the bioinformatic, behavioural and genetic methodologies that could be employed in clarifying the mechanisms and biology underlying alcohol dependence. It is very useful for researchers, clinicians, laboratory heads and managers from both biology and bioinformatics backgrounds, who use or intend to use microarrays or other transcriptomics technologies in analysing complex disease traits. This book s coverage is broad and ranges across most of the bioinformatics and genetics you will need to successfully analyse and validate DNA microarray data. It has evolved from my over three years of doctoral research on the genetics of alcohol addiction using Drosophila as a model, and thus would be suitable for researchers in the area at postgraduate or professional level. ····· 10361133123
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Osteoporosis is a systemic disorder characterized by decreased bone mass and microarchitectural deterioration of bone tissue, leading to bone fragility and increased susceptibility to fractures of the hip, spine, and wrist. Due to its important prevalence worldwide, osteoporosis is considered a serious public health concern associated with disability and pain. Osteoporosis affects over 200 million people worldwide. One in three females and one in eight males will develop osteoporosis. TreatmentThere are several medications used to treat osteoporosis, depending on gender. Medications themselves can be classified as antiresorptive or bone anabolic agents. Antiresorptive agents work primarily by reducing bone resorption, while bone anabolic agents build bone rather than inhibit resorption. Lifestyle changes are also an aspect of treatment. PreventionMethods to prevent osteoporosis include changes of lifestyle. However, there are medications that can be used for prevention as well. As a different concept there are osteoporosis ortheses which help to prevent spine fractures and support the building up of muscles. Fall prevention can help prevent osteoporosis complications. ····· 10361133095
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Catharanthus roseus is an important medicinal plant with the history of alkaloids exhibiting anticancerous property of which vincristine and vinblastine two dimmers forms are most important.The present study was undertaken to establish a reliable protocol of callus induction, somatic embryogenesis and its maintenance and also the study of potential of morphogenesis particularly somatic embryogenetic events by the action of various growth regulators at different concentrations and the subsequent study of these obtained somatic embryos at various temperatures. ····· 10361133056
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Ultraviolet B (UVB) radiation is the component of sunlight that damages DNA. Red-haired people are especially vulnerable to the damaging effects of UVB due to the low content of eumelanin in their skin. Accumulated damage from UVB can lead to skin cancer. A transgenic strain of mouse containing an inducible melanogenesis system was used to investigate the mechanism of protection of eumelanin. Melanogenesis in this murine model can be induced by the application of the diterpene, forskolin to the epidermis. Forskolin increases eumelanin protection by inducing the expression of cAMP, which then upregulates the expression of melanogenic genes. To assess the protection afforded by eumelanin to the epidermis, transgenic mice were exposed to varying doses of UVB in the presence or absence of forskolin induced melanin. DNA damage was assessed by immunohistochemical staining for cyclobutane pyrimidine dimers. Vehicle treated mice and albino mice showed thymine dimer formation at 20 and 50 mJ/cm^2 of UVB. Forskolin treated and black-skinned mice showed no thymine dimer formation at these doses. These results indicate direct UVB protection by eumelanin through a light filtering process. ····· 10361132997
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray In my research protocol I used slaughter house goat ovaries. The embryo transfer technology in goat can be successfully done by three ways, i) multiple ovulation and embryo transfer (MOET), ii) in vivo ovum pick up (OPU) and iii) oocyte recovery from slaughtered animal. Though the former two techniques are very much useful but they require huge involvement. So in vitro production (IVP) of goat embryo from slaughterhouse ovaries might be considered as a low cost and sustainable technology in Bangladesh condition. This technology allows the predictable supply of embryos from ovaries of slaughtered females or from live selected animals, via repeated recovery of primary oocytes. To date, this technique has given rise to considerable success in both cattle and buffalo, achieving a success rate ranging from 30-50% development. This technology does not only offer optimization of high-quality dams, but also allows the preservation and rapid multiplication of genetically superior characters by making embryos available for cloning, sexing and nuclear transfer. ····· 10361132851
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Information on genetic variation of breeding materials helps maintain genetic diversity and sustains long term selection gain. Marama bean [Tylosema esculentum (Burchell) Schreiber] occurs naturally in arid, dry parts of Southern Africa and due to the high nutrient value of the seeds and tubers, rich in protein, oil and starch, it is a potential crop for arid areas where few conventional crops can survive. Recently, the development of SSR enrichment techniques has increased the efficiency of SSR characterization in new species. The microsatellite regions of the genome were the main focus and the matK gene was also explored for its potential to carry out a marama bean genetic diversity study. Microsatellite loci were isolated from the marama bean germplasm using a modified FIASCO enrichment technique. Nine marama bean microsatellite libraries enriched for (AAG)7, (GTT)7, (AGG)7, (GAG)7, (CA)10, (CT)10, (TCC)7, (CA)15 and (CAC)7 were created. The matK gene product was found to be half the expected size of the gene found in other legumes. The found homology with Tylosema fassoglensis (trnK gene) and Pisum sativum (matK gene) suggests that an identical region was amplified. ····· 10361132807
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The network alignment has been formulated formally. While there are some variations among the tools, the key idea is similar: to combine gene sequence information and protein-protein interaction (PPI) network information to find conserved interaction regions across species. A biological interpretation of network alignment is to find functional homologues across different organisms. The general problem, known as the problem of finding common subgraphs across multiple networks, is NP-hard. Heuristic methods combining sequence, interaction and functional similarities have been developed to tackle it. In this book, state of the art introduction for network alignment is conducted from pairwise to multiple species. For pairwise alignment,HopMap and Mawish extension algorithms are presented with high specificity and sensitivity comparing to existing tools. For multiple alignment, the HopeMap-M alignment algorithm is able to align 10 networks with tens of thousands of proteins each in less than a few minutes. Then based on the framework of parametrized complexity theory, we derive parameterized complexity of Multi-MCS for various parameters on different classes of graphs. ····· 10361132737
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The present study was designed and carried out to investigate the role of connective tissue growth factor (CTGF) during eye development of CD1 mice at pre- and postnatal stage by using different technique as Real time PCr and Immunohistochemistry In conclusion CTGF is essential for life and absence of this gene lead to the death, Knockout homozygous CTGF -/- severe from a lot of abnormalties during prenatal stages until death. The over-expression CTGF transgenic mice with high concentration in line 6 showed a disappearance of the ciliary body processes, while the moderate over-expression CTGF of line 5 and low over-expression of line 1 showed abnormalities in the trabecular meshwork on the levels of immunohistochemistry that was accompanied with an increase in intraocular pressure and degeneration of optic nerve axons. So, we suggest that the over-expression of CTGF can cause the primary open angle glaucoma. The mice from line 1 and 5 can use as a model for primary open angle glaucoma diseases ····· 10361132696
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The purpose of the study was to examine the currently used two organophosphate pesticides Dichlorvos and Chlorpyrifos on Drosophila melanogaster, a non-target organism. The toxic effect was examined by the three major endpoints of oxidative stress. The fly mortality observed at the highest concentration of Dichlorvos indicates severity of the pesticide action on the organism. Such a drastic effect may be due the inhibitory effect of key neurotransmitter enzyme acetylcholinesterase resulting into irreparable damage to the vital cellular activities as reported earlier. The induction of key anti-oxidant enzymes Catalase and Superoxide dismutase and LPO activity indicates oxidative stress caused by the organophosphate pesticides in the exposed organism. Such a stress may arise due to generation of free radicals in the pesticide exposed flies. Another observation was that pesticide induced oxidative stress was maximum in the old flies supporting the earlier reports that aging causes more free radical generation and less quenching of free radicals. This study further emphasizes the utility of using fruitfly as a model for studying basic biological process in eukaryotes ····· 10361132657· 1 · ::::: · 4 ·· 5 ·· 6 ·· 7 ·· 8 ·· 9 ·· 10 · ::::: · 36 ·
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