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High-throughput Microfluidic Proteomics

für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Proteomics discovery holds the key to understanding biological process. Yet, millions of proteins with varied modifications and dynamic abundance pose a daunting measurement challenge. Facing the sea of proteins, the multiple sample preparation is the critical bottleneck which limits the power and speed of proteomics discovery. It is urgently calling for automatic, high throughput, and multiplexed protein processing platform. This book, therefore, introduces a state of the art of microfluidic technology for high-throughput proteomics. The functional nanoporous structures were created in microfluidic scale to form a new generation of multiple protein processing platform, including the preparatory (i.e., separation) and biological functions (i.e., enzymatic digestion). Such lithographically defined polymer materials possess the scaling-up capability for parallel, high-throughput protein processing. The strategy developed here should shed light on the advanced proteomics and glycomics, and should be especially useful to the exciting field of biomarker discovery, or anyone else who may be considering utilizing biotechnology for rapid, and ultra-low sample assay. ····· 10361117933

Estudio de la degradación del caucho natural por RMN de bajo campo

für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
El presente proyecto se realizó en el Instituto de Ciencia y Tecnología de Polímeros (CSIC). Su desarrollo tuvo como objeto estudiar detalladamente el proceso de degradación del caucho natural y la influencia que tienen los estabilizantes Vulkanox BHT y Vulkanox 4020 (6PPD), como agentes protectores, para diferentes sistemas de caucho vulcanizados con azufre y peróxido de dicumilo (DCP). Cada muestra fue sometida a ensayos mecánicos (tracción, dureza y resiliencia) y térmicos (calorimetría diferencial de barrido), y se estudiaron por resonancia magnética nuclear de bajo campo (RMN). Este proyecto o INFORME DE PASANTÍA se presentó ante la Ilustre Universidad Simón Bolívar como requisito parcial para optar al título de Ingeniera de Materiales en Enero de 2011. ····· 10361117591

Diferentes estrategias para la búsqueda de compuestos antifúngicos

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
El incremento de pacientes inmunocomprometidos y los numerosos inconvenientes de las drogas antifúngicas existentes actualmente en el mercado farmacéutico crean una urgente necesidad del descubrimiento de nuevas drogas para el tratamiento de las micosis. Entre las numerosas familias de compuestos que han sido evaluados con este objetivo, maleimidas N-sustituidas han demostrado ser excelentes candidatos para la generación de una nueva familia de antimicóticos. Por este motivo, un amplio panel de maleimidas y análogos fueron obtenidos y evaluados por su actividad antifúngica. La obtención fue realizada por síntesis química y por biotransformación, estrategia que demostró ser útil para la generación de compuestos activos y para la síntesis diastereo- y enantioespecífica. La actividad se determinó por metodologías estandarizadas, complementada con la evaluación del poder fungicida, espectro de especies susceptibles, mecanismo de acción y de la estabilidad de los compuestos. El análisis de la relación estructura-actividad permitió identificar los requisitos estructurales necesarios para la actividad y seleccionar los compuestos más promisorios para el desarrollo de nuevos antifúngicos. ····· 10361117207

Vinilsulfonas

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Las vinilsulfonas constituyen una amplia familia de compuestos cuya reactividad las ha convertido en intermedios útiles en síntesis orgánica así como en efectivos inhibidores de ciertos procesos enzimáticos. Sin embargo, las enormes posibilidades que ofrece este grupo funcional para interconectar de forma covalente diferentes componentes moleculares se explotan en esta Tesis Doctoral desarrollando aplicaciones destacadas en diferentes campos que incluyen: (i) marcaje de proteínas con etiquetas electroactivas como el ferroceno (ii) inmovilización de proteínas en soportes como la sílica (iii) transfección génica, modificando con compuestos de carácter lipídico un dendrímero aminado como el PAMAM (iv) catálisis, debido a la importancia que ha adquirido la click-chemistry se han desarrollado eficaces catalizadores heterogéneos (magnéticos y no magnéticos) para la reacción de cicloadición de azidas y alquinos, minimizando la contaminación en los productos finales y pudiendo emplear estos catalizadores incluso con biomoléculas. ····· 10361116819

Contextualización Curricular para la Enseñanza de la Química Escolar

für 88.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
`El tema abordado en este libro es de gran relevancia para el área educacional de Chile, ya que vivimos actualmente un proceso de cambios en la sociedad, en la escuela y en consecuencia en el curriculum nacional, desde donde se entiende la necesidad urgente de intentar caracterizar el proceso de contextualización curricular, en el especial en lo que se refiere en el área de las ciencias.` Carol Joglar Campos Mg. en Ciencias y Matemáticas, Brasil. `El libro aborda un tema relevante para la investigación curricular, aportando elementos que podrían enriquecer la discusión teórica del concepto contextualización curricular desarrollando un proceso indagativo claro y riguroso.` Olga Espinoza Aros, Dra. en Educación, Pontificia Universidad Católica de Chile. `La temática presentada es de un alto valor en la perspectiva de indagaciones sobre las representaciones epistemológicas, didácticas y científicas que poseen los docentes acerca de la enseñanza de la química y su aplicación en el aula. Investigación que aporta teórica, metodológica e institucionalmente elementos para generar propuestas innovadoras.` Mario Quintanilla Gatica. PH, D Science Education. ····· 10361116700

La biotecnología como proyecto de sustentabilidad

für 35.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
En los últimos 35 años, desde todos los ámbitos de la sociedad, económicos, políticos y científicos se ha ido tomando en cuenta la limitación de los recursos naturales y por tanto, la necesidad de elaborar planes, estudios y proyectos de investigación dirigidos a desarrollar políticas que permitan su uso eficaz y racional. Dentro de este grupo de recursos no renovables se encuentra el gas natural y es por tanto que se buscan nuevas alternativas energéticas lo que íntimamente se está relacionando con el tratamiento anaerobio de ciertos residuos, sobre todo de aguas residuales, ya que en este punto el agua antes considerada un recurso renovable debido a su abundancia y fácil disponibilidad por múltiples factores ya ha sido afectada y ha pasado a convertirse al otro grupo. Para solucionar los graves problemas en el campo de fuentes renovables de energía y situaciones existentes contra la sustentabilidad, hay un área multidisciplinaria: Bioteecnología. Aquí podrás enterarte como la biodegradación anaerobia conjuga medios que la misma Tierra nos proporciona con las ciencias e imaginación para promoveer fuentes alternativas de energía que promueven la sustentabilidad en nuestro planeta. ····· 10361116666

Relación entre las propiedades magnéticas y la actividad catalítica

für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Las reacciones catalíticas heterogéneas, se llevan a cabo en los centros activos de la superficie del catalizador, en estos sitios activos se encuentran los átomos que participan en el mecanismo de reacción catalítica y a su vez la actividad catalítica del catalizador depende del carácter de estos átomos en los centros activos, por lo tanto dicha actividad debería estar relacionada con el comportamiento magnético y la distribución catiónica de los átomos presentes. ····· 10361116623

Hacia el Desarrollo Sostenible

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
La degradación ambiental se ha convertido en un importante problema al que deben enfrentarse la ciencia y la tecnología. Los temas tratados en este trabajo, pretenden aunar, con la introducción de los líquidos iónicos en distintos procesos, la preocupación por el medio ambiente y las inquietudes constantes del progreso. Es por ello que a lo largo de esta tesis se ha desarrollado nuevos sistemas catalíticos basados en líquidos iónicos, que seguidamente se han aplicado a procesos químicos de interés como la transposición de Beckmann de oximas cíclicas, reacciones de acoplamiento C-C tipo Heck y reacciones de formación de enlaces C-C tipo Knoevenagel, Claisen-Schmidt, adición de Michael y Henry. ····· 10361116600

Estabilidad química de relaves y escorias

für 32.31€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Para asegurarse de que algunos residuos mineros masivos no generen importantes impactos ambientales, es necesario identificar y evaluar los potenciales riesgos ambientales asociados a estos residuos, los que están determinados por las características propias y por las condiciones del lugar de disposición. En este estudio se utilizaron cuatro tests de lixiviación para determinar la estabilidad química de relaves de flotación y escorias de fundición. Adicionalmente, se determinó el potencial de generación y neutralización de drenaje ácido, y se realizaron diversos experimentos para estudiar la influencia de otros parámetros en la estabilidad de este tipo de residuos. Los resultados demuestran que la estabilidad química y/o peligrosidad de este tipo de residuos no sólo se determina en función de su lixiviabilidad y de la cantidad de metales que eventualmente se pueden disolver a partir de ellos, sino también de otros parámetros como el pH en pasta de la muestra, el potencial de neutralización, el tipo de solución lixiviante, el grado de liberación de los minerales sulfurados y el volumen de solución que lavará la muestra. ····· 10361116551

Supramolecular Photoactive Systems

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Chemists deal with matter and its transformations. They create chemical species into an infinite variety of combinations, at least until they have imagination. Some of them hold chemical species together trying to gain control on increasing matter complexity. Supermolecules are organized entities resulting from the self-assembly of two or more chemical species held together by intermolecular forces, thus representing a further step towards complexity compared to molecules as the latter do to atoms. Novel properties peculiar of the supramolecular systems thus arise and do not result from the simple superposition of those of the component units. Self-assembly of chemical species by weak, non covalent interactions is a widespread concept to Nature`s forms and functions and is attracting increasing interest in artificial systems conceived to control mechanical movements, process information, and harvest sunlight. The present PhD thesis studies some supramolecular photoactive systems that act as antennas capable of collecting incident light and transfer excitation energy or electrons from one molecular component to another. ····· 10361116154

Photolysis of Tris(ethylxanthato) Chromium (III) complex in DMSO

für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
In the present work we prepared tris(alkylxanthato)chromium(III) and intended to study the photochemistry of these complexes in dimethyl sulfoxide. These complexes might be useful in many applications. Moreover, metal chelate with metals at high oxidation state is active in the enhancement of photodegradation of plastic and therefore, might serve as photocatalyst to treat the plastic waste pollution problem. The effect of number of methyl group in these complexes has been also studied. This work also deals with the photochemical reaction and determination of quantum yields and reactivity ratios of the photodecomposition processes of the different complexes in DMSO. Spectroscopic methods have been used for the elucidation of the photochemical reactions, and determination of the quantum yields of the photochemical decomposition processes. ····· 10361115930

PHYTOCHEMICAL AND PHARMACOLOGICAL SCREENING OF Xanthium indicum

für 35.91€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Ethanolic extract of Xanthium indicum plant was prepared and tested for its phytochemical and pharmacological investigation. Preliminary phytochemical screening showed that extracts possessed the active principles-alkaloid, carbohydrate, glycoside, flavonoid & Tannin. The extract showed antioxidant property(IC50 ==136.45 µg/mL) compare to standard (ascorbic acid, IC50 =12.16 µg/mL). The extract also shows antioxidant activity by reducing FeCl3. The extract inhibited the acetic acid induced writhing in mice (47.5% P ····· 10361115816

Nanostructured Polymers

für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
It is this ability to design and characterize materials at the nanoscale that distinguishes modern nanotechnology from previous activities in materials science and chemistry. The drive behind nearly all these efforts is the continued development of nanostructured materials, and the constant stream of new properties and capabilities that are being discovered. By being able to fabricate and control the structures of nanoparticles, the scientist and engineer can influence the resulting properties, and ultimately, design materials with desired characteristics. The undertaken synthesis and characterization work of the nanosized materials encompasses the advantage of better perceptive of the underlying chemical functionality of the molecules that can be controlled and almost infinitely varied, which shall enable to achieve this goal easier and form the ground for future nanotechnological devices. ····· 10361115729

CERIA BASED NANO CATALYSTS

für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
There has been a sustained interest in the development of new catalysts having advantages to the major global problems like air pollution and other environmental issues. Three-way catalysts (TWC) for automotive exhaust treatment, which transform three environmentally hazardous gases namely CO, NOx and hydrocarbons to environmentally less hazardous form, is therefore a topic of intensive research. Ceria (CeO2) is an important ingredient in the formulation of TWC. The oxygen storage/release capacity (OSC) of ceria plays a vital role in this regard. Many technological and bioapplications have also been benefited from the unique redox and transport properties of ceria and ceria-based materials. This book emphasizes the design and evaluation of some unsupported and supported ceria based mixed oxide catalysts for catalytic applications, especially CO oxidation reaction. ····· 10361115673

Graphene: synthesis and applications

für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
As an exotic material of the 21st century, graphene attracted a global attention in the fields of science, medicine and engineering. Graphene is the thinnest known material showing high electrical and thermal conductivity, mechanical flexibility, optical transparency, and low coefficient of thermal expansion behavior. There is different kind of approaches to produce graphene, including chemical and physical methods. Obviously the exceptional properties of graphene are extremely dependent on the exfoliation of the graphite to one-atom-thick planar sheet and defect less structure of graphene. This book explains various methods to produce graphene sheets with excellent properties and approaches to prevent the aggregation. Additionally, it focuses on physical, chemical and biomedical applications of graphene. ····· 10361115627

Peptide Nucleic Acids and Markers

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
The remarkable binding properties of Peptide Nucleic Acids (PNA), the so called artificial DNAs, have spawned a rapidly expanding new field of research, where the targets are the synthesis of PNAs and PNA analogues, and their applications as therapeutics, DNA diagnostics, tools in biotechnology and much more. PNA is linked to various scientific disciplines, few includes medicinal chemistry,biochemistry, molecular biology, immunology and drug development. This book describes the design, synthesis and analytical studies of labeled nucleic acid analog. Basic methods for the synthesis of PNA monomer/oligomer are incorporated. Further, the syntheses of electrochemical and fluorescently labeled PNA monomers/oligomers are dealt-with in detail. The final part of the book discusses about the possibility of using linkers/spacers to carry marker to link PNA monomer/oligomer. This book would be an inspiration for undergraduates/postgraduates and experienced researchers as it provides an easy introduction to the optimal use of PNA in various disciplines. ····· 10361115585

Modelling of Biosensors

für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Biosensors are analytical devices for selective detection of an analyte or a group of analytes that combine biological material with a physicochemical detector, yielding a measurable signal. Biosensors are used in various fields of human activity, including environmental and clinical analyses, food analyses and control of industrial processes. Most efforts in biosensor studies have been focused on the fabrication of various combinations of biological components and measuring systems less attention has been paid to the interpretation of factors, affecting the formation of biosensor output signal and the problems of biosensor calibration. So in many cases only a fraction of potentially available information is taken into consideration, making the biosensor analyses less reliable than they actually could be. The present work is an effort to solve some of the problems in biosensor signal analysis, proposing a new approach to signal modelling and calibration of biosensors, based on oxidoreductases just to promote the application of these biosensors for on-line analyses. ····· 10361115548

FORMATION OF HgCdTe (MCT) BY ELECTROCHEMICAL ATOMIC LAYER DEPOSITION

für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
HgCdTe or Mer-Cad-Tel is the most widely used Infrared material. The present study describes the growth of MCT via Electrochemical ALD, using an automated electrochemical flow cell deposition system. Deposits were characterized using X-ray diffraction (XRD), electron probe microanalysis (EPMA) and reflection absorption Fourier transform Infrared spectroscopy (FTIR). As deposited films showed a strong (111) preferred orientation. Changes in deposit composition showed the expected trend in band gaps: the more Hg the lower the band gap, but with some significant deviations. Electrochemical quartz crystal microbalance (EQCM) studies, using an automated flow cell, indicated that some deposited Cd was stripping at potentials used to deposit Hg. In addition, redox replacement of deposited Cd for Hg was evident, a function of the greater stability of Hg than Cd. ····· 10361115207

Doped Transition Metal Oxide and Ferrite Nanocrystals

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Nanosized magnetic materials have received great attention and importance during the last decade. Nanomagnetic material is one of the hottest subjects of present day research activities. The physical properties of nanosized magnetic materials differ considerably from that of their bulk counterparts and the magnetic characteristics of many materials can be tuned by reducing their size. The objectives of this research work are the synthesis and studies on the structural and magnetic properties of some selected transition metal oxides and ferrites in nanocrystalline form. The research work has been carried out on transition metal ion doped zinc oxide (ZnO) based diluted magnetic semiconductors (DMSs), some ferrites (for instance, Zn-ferrite, NiZn-ferrite, maghemite, etc.) and magnetopolymer nanocomposite systems. The respective nanocrystalline oxides are synthesized using a simple solution combustion method and characterized using various techniques. The results from the studies on different materials are presented in this thesis, consisting of six chapters. Last but not the least, several performance parameters have been measured and conditions for best results have been discussed. ····· 10361115119

Hazardous Chemicals

für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Chemical Hazardous cover a wide spectrum of chemicals including explosives, flammable chemicals, corrosives etc. There are more than 70,000 chemicals in use with another 500-1000 added each year. Many of these chemicals are categorized as hazardous and they are often subject to chemical regulations. Mitigating the risks associated with hazardous materials may require the application of safety precautions during their transport, use, storage and disposal. Many legal requirements have been introduced into international legislation over the years to protect people and the environment from the potential adverse effects of exposure to hazardous chemicals. However, although significant reductions in pollution from major industrial sources have been made, basic information on the public health and environmental hazards of many chemicals placed on the market for use in manufacturing processes and in everyday products is still lacking This book summarizes the common hazardous chemicals in use and methods of identification based on the Globally Harmonized System of Classification and Labeling of Chemicals. ····· 10361115005

Construction of ISEs for Some Drugs and Its Analytical Apllications

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
This study includes the determination of Trifluoperazine hydrochloride (TFPH) and Tetracaine hydrochloride (TCH) drugs by conventional ion-selective electrode (ISE) and flow injection potentiometry (FIP). Chapter one describe general introduction about ISE and FIP with review of its applications in pharmaceutical analysis. While chapter two describe chemicals, apparatus, preparation of standard solutions, and construction of membrane electrodes. Chapter three and four showed the results and discussion of TFPH and TCH ion-selective electrodes. The electrodes were characterized in terms of composition, usable pH range, life span, response time and the selectivity coefficient. The best electrodes were successfully applied for the determination of TFPH and TCH in pharmaceutical formulations. Chapter five and six describe the results and discussion of TFPH and TCH PVC-based membranes containg the ionophores -, - and -cyclodextrins, dibenzo-18-crown-6 and dibenzo-30-crown-10 ether and their response towards TFPH and TCH using FIP. A FIP condition was also studied. The best sensors were applied to the determination of TFPH and TCH in pharmaceutical preparations and human urine. ····· 10361114993

Ruthenium based Fischer-Tropsch Synthesis

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
The Fischer-Tropsch (FT) synthesis is the catalytic conversion of hydrogen and carbon monoxide into higher hydrocarbons. Although ruthenium is the most active catalyst in FT synthesis, the lower cost metals iron and cobalt are used commercially. Generally, increased catalyst performance is achieved with increased metal surface area and dispersion, though recent literature reports that cobalt, iron and rhodium crystallites below a certain size in the nanometer range display lower metal surface area specific activity and a high methane selectivity. There have also been several attempts to investigate the possibility to conduct a homogeneously catalysed FT synthesis, which can be considered as an extreme case of metal dispersion. The aim of this study is to investigate FT activity and selectivity on well-defined nano-sized ruthenium crystallites and supported organometallic clusters with varying nuclearity, and to compare/bridge the obtained findings by subdividing it into a) catalyst preparation and characterisation, b) FT performance of model catalysts and c) theoretical investigations of the feasibility of FT reactions on ruthenium complexes. ····· 10361114952

Functionalized Silica Gel as Metal Scavenger, Sensor, and Catalyst

für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
A wide variety of novel materials can be prepared through the chemical modification of silica gels. In addition to their use in chromatographic separations, they have been increasingly used as catalysts in liquid phase organic reactions. The application of these materials results in viable and more environmentally friendly alternatives to traditional homogeneous catalysts. The present monograph describes the synthesis of two functionalized silica gels for highly specific separation and preconcentration of metal ions followed by their applications as sensors and as catalysts. ····· 10361114830

Polymeric Coatings

für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray
Metallic and non-metallic coating methods have been developed in order to improve the operating time of materials . Coating of metal surfaces with polymeric materials is one of the commonly used methods to protect the metals from corrosion. The synthesis of new polymeric materials having complex properties, especially coating such as, has recently become of great practical importance to polymer chemistry and technology.Anticorrosion coatings,aggressive conditions, must be resistant to chemical attack, should have high adhesion properties. The synthesis of new materials can be prepared by either their monomers or modification of used polymers in industry. As it is known, corrosion of metals under aggressive conditions causes very big economical losses.Therefore, using cheap polymers and huge amount of industrial wastes as raw materials has theoretical and practical value in order to coat the metal surfaces with corrosion resistance polymeric materials.The literature information and our efforts, aggressive condition for corrosion protection of metals,surface coatings polimeric has determined that it has great practical importance. ····· 10361114525

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