für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Angiogenic and apoptotic activity plays an important role in the development and progression of soft tissue sarcoma. Both anti-apoptotic and pro-apoptotic activity are directly associated in tumor cells and endothelial cells in this study supporting the role of endothelial cells in survival and regression of tumor cells in tumoregenesis. Thus, the inhibition of endothelial cell survival factor or activation of endothelial cell death is a promising prospect as a candidate for tumor therapy. We also demonstrate that anti-apoptotic activity is associated with tumor histologic subtypes which are commonly seen in synovial sarcoma. In addition, there is also diversity seen in angiogenesis and pro-apoptotic activity amongst the various histologic subtypes of STS eventhough it is not statistically significant. This indicates the potential of the above protein expression as a useful marker for diagnosis of specific histologic subtypes. We also have shown that high angiogenic activity is correlated with weak apoptotic activity. This indicates that increased angiogenic activity may inhibit apoptotic tumor cells death which leads to cell proliferation. ····· 1036199751
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The book is designed for an educated reader, as well as for all those involved in medicine and interested in heart attacks. The aim of the book is to introduce the reader to the causes that may underlie the disease, so as to prevent its progress. The authors analyze the mechanism of the progressing of atherosclerosis with focus on the disorders in the lipid blood composition which, among other things, determine the development of the disease. The language of the book is easy to understand. The book is suppled with a vocabulary of the major medical terms. ····· 1036199710
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Cigarette smoking has led to epidemic level increase in the progression of atherosclerosis, chronic obstructive pulmonary disease, cardiovascular disorders and cancer. The effects of smoking on human health have been investigated for the last hundred years, but the exact pathophysiological mechanisms responsible are yet to be completely elucidated. In the present study, effects of smoking on hematological parameters, inflammatory markers, antioxidants, markers of hemostasis and fibrinolysis were investigated among chronic smokers and compared with nonsmokers and ex-smokers. The results of present study indicate oxidative-antioxidants imbalance, low grade inflammatory response alterations in the markers of reheology, coagulation and endothelial functions, which increase the chances of cardiovascular disorders among smokers. Although these smoking induced effects may persist for many years most of these alterations return back to normal values within 2-5 years of smoking cessation. Therefore immediate smoking cessation is strongly recommended to smokers as quitting smoking increases life expectancy by reducing the health care risks. ····· 1036199709
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray A community based cross sectional study was conducted from October to December 2004 in in Afar Regional state, Ethiopia to assess factors influencing utilization of maternal health care services. Analysis revealed that 79.6% of the women had at least one prenatal visit during their recent pregnancy. Most of the antenatal care (ANC) attendants made their first visit during their second trimester of pregnancy. Among ANC users 53% of had less than four antenatal care contacts. Majority of deliveries took place at home, of which 93.7% were attended by TBAs. Absences of a health problem, lack of awareness, work overload, and distant health service were the main reasons for no ANC attendance. . In conclusion, the study revealed low maternal health care utilization in the area. Demographic and socio cultural factors were found to be barriers to utilization of maternal healthcare services. Increasing maternal health service coverage and promotion of IEC in the community are recommended. ····· 1036199687
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Ankle injuries are unique as they are not only intra-articular in weight bearing joint, but also caused by a variety of mechanism, each resulting in different pattern with ankle fractures. The primary concern is residual instability of the joint as malalignment or residual displacement can adversely affect the biomechanical behaviour of ankle and resulting loss of function, due to non restoration of normal anatomy. Therefore essential of proper anatomical parameters for assessment of reduction and improved designs of implants used to get good results. The unique measurement of angles on both surface of malleoli and other parameters definitely contribute for assessment of reduction and prognostic evaluations of ankle fracture,Designing,mouldingand manufacturing of prebent plates for use in distal ends of tibia and fibula. ····· 1036199663
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This study aims to determine the optimum storage temperature and time for Prothrombin time and activated Partial thromboplastin time at various intervals at both room temperature and refrigerator. This study was approved by the Ethics Committee of AMDI in USM. After obtaining the consent, 33 blood samples were collected from AMDI staff and students. Prothrombin time (PT) was measured at 0, 4, 8 and 24 hours (h). Partial thromboplastin time (APTT) was measured at 0, 2, 6 and 8 h both at room temperature (RT) and refrigerator. Thirty three subjects (14 males and 19 females, aged from 20 to 40 years) were involved. PT showed no significant differences at RT at 4 h, while significant differences after 8 h and 24 h at RT and after 4 h, 8 h and 24 h at refrigerator were observed. APTT showed no statistically significant differences at 2 h but showed significant differences at 6 h, 8 h at both RT and refrigerator. It can be concluded that samples for PT testing can be accepted only up to 4 h when kept at RT while the samples cannot be accepted when kept at refrigerator for 4 h and above. APTT samples can be accepted up to 2 h only at RT or refrigerator. ····· 1036199635
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Progesterone is a hormone normally secreted by the body in pregnancy is required for the viability of the pregnancy. High dose progesterone is known to cause neural tube defects (NTDs) in certain animals.In humans, exogenous high dose progesterone may be administered during in-vitro fertilization and in Intracytoplasmic sperm injection treatment. Studies on the teratogenic effects of progesterone have dealt mostly with the possible masculinising effect on the female fetus. Other abnormalities that have been described with the use of progesterone are cardiac malformations, the effects on the central nervous system, like neural tube defects and development of Amelia. Around the world, there are hundreds of thousands of pregnancies affected each year by NTDs, with some fetal demise through spontaneous or induced losses. Based on animal studies, epidemiologic studies and intervention trials, maternal folic acid (vitamin B9) is known to be protective for NTDs, primarily spina bifida and anencephalus. The purpose of the present study was to describe the effect of HDP alone, or in combination with folic acid, on occurrence of NTDs in chick embryo. ····· 1036199595
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Cholelithiasis & its complications are the leading cause of surgical entry into the peritoneal cavity in Northern India. So rife is this disease in this part of the world that Cholecystectomy is perhaps the single most commonly performed routine surgical procedure. Throughout the recent history of modern surgery, the one general surgical technique that has generated immense excitement & rapidly percolated into mainstream of surgical practice, is none other than-Laparoscopic Cholecystectomy. The technique thou born in secrecy & developed under an atmosphere of skepticism & hostility, has triumphed the world & mind of surgeons. This technique has become the treatment of choice & gold standard for the management of gall stone disease. But like Shakespeare`s famous phrase Uneasy lies the head that wears the crown , this technique too has some associated fallacies. Alteration in serum liver enzymes induced by laparoscopy has been largely underestimated, and the aim of this study is to compare & evaluate hepatic function in traditional Open vs Laproscopic Cholecystectomy. ····· 1036199536
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The Book On Gap Analysis of Laboratory Services For Accreditation By College Of American Pathologists gives an overview of CAP accreditation norms. it is useful for management students doing their Masters in Hospital Management and specially for those who wants to go into Hospital Quality Management. I did this project as a part of my dissertation work in one of the most reputed Hospital of India Kokilaben Dhirubhai Ambani Hospital. I got to learn a lot from this project and now i want to publish this for learning purpose specially for hospital management graduates. ····· 1036199478
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This book contains complete information about formulation and evaluation of omeprazol pellets (delayed release). Firstly it contains various methods of pellets formation along with its evaluation followed by drug profile (omeprazol). The drug profile contains its evaluation using various parameter like cars index, solubility, melting point, solubility, dissolution etc, which is utilized for its pre- formulation and evaluation. Finally a stable formulation is chosen for the various formulation made and is used for omeprazol pellet formation (delayed release). ····· 1036199458
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray During the past 50 years, more than 100 000 compounds have been screened but only seven plant-derived anticancer drugs have received Food and Drug Administration (FDA) approval for clinical application. Identification of agents that are pharmacologically active against human cancer has depended largely on the screening of natural products and their analogs. Many anticancer drugs have been discovered fortuitously through random investigation of organisms indeed, serendipity remains important in anticancer drug discovery. Although it is broadly accepted that cancers comprise an evolutionary microcosm, this idea has not been advanced to understand and control carcinogenic progression. Development of high throughput isolation of components from a crude natural product extract using highly automated separation techniques has enabled chemists to speed up the isolation, purification and characterization process. These modern techniques coupled with high throughput screening systems are expected to yield a lot more number of lead structures in the near future ····· 1036199438
für 35.91€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Aesthetic Surgery-Current Perspectives This book provides a comprehensive, simplified, practical and recent analysis on popularly practiced cosmetic surgeries. It deals with all aspects of aesthetic procedures with special emphasis on bariatric surgery. The highlights of the book is the coverage of topics like facial aesthetic surgery, breast reconstruction, liposuction, botox/ fillers, rhinoplasty, hair transplant and skin grafting, all in one book. ····· 1036199428
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The book: Cafergot and its effect in sickle cell erythrocytes: is an excellent book designed to provide concise summary of in vitro effect of cafergot in sickle cell erythrocytes. Cafergot is an egort alkaloid and adrenergic blocking agent used in the treatment of migraine headache. In this book, it was observed that cafergort has an adverse effect in sickle cell erythrocytes. It is a research oriented book and it would be very helpful to researchers,scientists,medical doctors,as well as undergraduates in higher institutions. ····· 1036199424
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Estrogens are important regulators of neuronal cell morphology and this is thought to be critical for gender-specific differences in brain function and dysfunction. Dendritic spine formation is dependent on actin remodeling by WAVE1 protein, which controls actin polymerization through the Arp-2/3 complex. We show that 17-estradiol (E2) administration leads to phosphorylation and redistribution of WAVE1 at sites of dendritic spine formation. WAVE1 phosphorylation is found to be triggered by a G i/G protein-dependent, rapid extranuclear signaling of ER to Src/Rac1/Cdk5 that directly phosphorylates WAVE1. After WAVE1 phosphorylation, the Arp-2/3 complex concentrates at sites of spine formation, where it triggers the local reorganization of actin fibers. In parallel, E2 recruits a G 13-dependent pathway to RhoA and ROCK-2, leading to activation of actin remodeling via moesin. Silencing of WAVE1 or of moesin abrogates the increase in dendritic spines induced by E2. In conclusion, our findings indicate that the control of actin polymerization and branching via moesin or WAVE1 is a key function of ER in neurons, which may be particularly relevant for the regulation of dendritic spines. ····· 1036199417
····· lezzter Preis 44.10€ ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This book presents a contemporary approach in the diagnosis, follow-up, treatment and care of Duchenne/Becker muscular dystrophy. Modern genetic tests are used to clarify molecular defects in our patients and to prepare them for future gene therapies. This is the first characterization of the cognitive impairment in Bulgarian patients with dystrophinopathy. The findings of the present study demonstrate that the cognitive profile of patients with dystrophinopathies is characterised by a broad range of intellectual abilities, as in addition to borderline general intellectual abilities, verbal short-term memory, is more severely affected than the long term one. A significant difference was found between general cognitive abilities in patients with an intact Dp140 isoform versus patients whose deletion was incompatible with formation of intact Dp140. ····· 1036199413
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This research is regarding bone turnover and its association with vitamin D blood levels in adult females. To date, this is the first study exploring the bone health status of apparently healthy adult females residing in Pakistan measuring bone turnover marker using NTx along with 25OHD and iPTH in blood. The highlighted findings of the research are high bone turnover as depicted by levels of serum NTx. Increased serum NTx is reported in 40.5% of the study population. Bone turnover is high among apparently healthy adult females regardless of vitamin D status. This high bone turnover is one of the mechanisms which can lead to osteoporosis in later life. ····· 1036199371
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The goals of the present work are to evaluate the sensitizing/protective effect of melanin in the cytotoxicity and genotoxicity of ionizing radiation, including induced oxidative stress modulation in malignant melanoma cells in presence and absence of melanin, and to interpret obtained results in the perspective of melanoma or other malignancies radiotherapy. The biological effects of ionizing radiation interaction are explored with special focus on the biologic effects of radiation in normal and melanoma cells and the interaction of melanin with the damage caused by ionizing radiation (IR). Melanin is a class of pigments present in almost all living beings. Melanin protection against UV radiation is widely acknowledged, but not completely understood some recent studies claim that melanin can also play an in important role in protection against ionizing radiation. However, other studies evidenced that melanogenesis may be a source of reactive substances, some of them carcinogenic. This study is an attempt to clarify which behavior prevails in IR-exposed cells. ····· 1036199355
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Diabetes is a common disease prevalent in both developed and developing countries associated with morbidity and mortality. In India the prevalence of diabetes is 12- 17% in urban and 2.5% in the rural population. Onset of type II diabetes occurs at a younger age among Indians, thereby giving ample time for development of the chronic vascular complications. Prevalence of the complications is higher in low socio-economic groups due to lack of glycemic control. Bacterial infections of the foot are commonly encountered in diabetic patients in clinical practice. Early recognition of lesions and prompt initiation of appropriate antimicrobial therapy is essential for controlling the infection and preventing morbidity. Diabetic foot infections are the leading cause (85%) for non traumatic lower extremity amputations. The sensitivity of organisms to drugs change over time, due to development of resistance and hence periodic surveillance studies will provide data for management of diabetic foot infections.This will benefit the postgraduate students and physicians in clinical settings. ····· 1036199331
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The scenario regarding potentially malignant disorders has recently been complicated by the increasing incidence of squamous cell carcinoma of the oral cavity in the younger population without any clear etiology. The changes may be at the molecular, genetic or immunologic levels. Nowadays, the importance of tumor markers is being increasingly felt for diagnostic and prognostic purposes in such conditions. SIBLING proteins play an important role in immune mechanisms and help in regulatory pathways of the body. Osteopontin induces endothelial cell migration and acts in subset of migratory pathways.It also play a important role in the process of angiogenesis. In this book, immunohistochemical role of OPN as a SIBLING protein has been studied, & its role in diagnosis and prognosis of Oral premalignancies and malignancies has been discussed. ····· 1036199319
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Essential hypertension is a major health hazard, if left undetected and untreated can lead to cardiovascular abnormalities with increased risk of morbidity and mortality. Hence it becomes necessary to identify the possible risk factors, detect at an early age and take suitable measures to reduce the cardiovascular complications. The study was done to evaluate the autonomic functions in normotensive children of hypertensive parents. Normotensive children of hypertensive and normotensive parents in the age group of 15 to 25 years were included in the study. Autonomic functions were evaluated by standardized methods. The results were analyzed using suitable statistical method. There was a demonstrable alteration in the autonomic function with reduced parasympathetic response coupled with enhanced sympathetic response in children of hypertensive parents. It was also evident that alteration in autonomic functions sets in during early adulthood in asymptomatic children of hypertensive parents. The autonomic function test can be used as a screening tool in later part of childhood and also during adulthood to detect the possibility of developing essential hypertension. ····· 1036199296
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The birth of a child with malformation gives rise to a mixture of strong feelings and often makes us search for an explanation for its occurrence. Since human reproduction is a complex process, congenital abnormalities can occur due to errors at any stage of embryogenesis. This book discusses the classification of malformations and incidence of malformations of the different systems. It gives a clear description of its etiology and also discusses the genetic aspect of the malformations. Various methodologies for holistic evaluation of congenital malformations include epidemiological studies, cytogenetic evaluation and animal experimentation. The present study shows that many human malformations arise because of the interplay of precisely timed genetic and environmental interactions, though some of them may be solely genetically determined. Based on the results and analyses of the present study management strategies are recommended to prevent, diagnose or treat the congenital malformations. ····· 1036199253
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Gingival Desquamation is a clinical manifestation in many inflammatory and immunological disorders. Although, Oral lichen planus, pemphigus vulgaris and mucous membrane pemphigoid accounts for majority of cases of gingival desquamation, but rare case such as Linear Ig A disease, Plasma cell gingivitis, tuberculosis and chronic ulcerative stomatitis should also be taken into consideration. Gingival Desquamation may present as the only manifestation in some cases, while, it may be associated with other oral and extra oral manifestations, like wickham`s striae in lichen planus, Nikolsky`s sign in pemphigus vulgaris, Ocular involvement in mucous membrane pemphigoid which help in diagnosis. In such cases, the patient should be referred to the concerned specialists for extra oral lesions. Cases where gingival desquamation is the only presenting feature,should be carefully taken care of, as they can mimic plaque induced gingivitis.Thus, familiarisation of various clinical presentation of gingival desquamation is essential for early diagnosis and treatment planning.This book, deals in detail the various causes for gingival desquamation, along with the histopathological features. ····· 1036199194
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray In Myanmar, tuberculosis is one of the major public health problems and recent estimates suggest that 1.66% of Myanmar population become infected with tuberculosis every year. The common causes of pleural effusion in Myanmar are tuberculosis and bronchogenic carcinoma. Evaluation of exudative pleural effusion includes studies of pleural fluid and blind needle biopsy of pleura using Abram`s pleural biopsy needle or Cope`s biopsy needle. However following these procedures some patients are still undiagnosed. Correcting this diagnostic deficiency the author`s main interest is pleural fluid Adenosine deaminase to search for tuberculosis in pleural space. Within the study period, 187 patients with various causes of pleural effusion admitted to the Department of Respiratory Medicine, Yangon General Hospital, Myanmar were studied. In this study, the author found out pleural fluid Adenosine deaminase assay is highly sensitive and specific test suitable for rapid diagnosis of tuberculous pleural effusion. ····· 1036199191
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray It is a retrospective study of homicidal deaths brought for Medico Legal Autopsy at the Forensic Medicine Department, M.P. Shah Medical College, Jamnagar, Gujarat (India) during the five year period from 2000 through 2004. This medical college is one of the most reputed & oldest post graduates institute & it caters over a vast region comprising of more than 6-7 districts of western part of the state. The study was carried out from the post mortem reports, police inquest papers, dead body challans, etc. available & details were also noted down from case history obtained from the relatives, eye witnesses, police investigating officers, hospital records etc. Homicide in the present study means any unnatural death resulting from the act of another person falling under sec. 302, IPC (Indian Penal Code). Records on each case were examined to determine factors such as age, sex, marital status, methods used, body injuries, causes of death, motives and any contribution of mental illness, alcoholism & sexual offences. The results were tabulated for easy study & comparison. ····· 1036199137· 1 · ::::: · 33 ·· 34 ·· 35 ·· 36 ·· 37 ·· 38 ·· 39 · ::::: · 74 ·
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