für 50.00€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Im deutschen Recht wird der Embryo mittels des Kriteriums der entwicklungsbiologischen Totipotenz definiert. Aber bei der Reprogrammierung somatischer Zellen in induzierte pluripotente Stammzellen ist gegenwärtig nicht gänzlich auszuschließen, dass diese Zellen ein temporäres Stadium der Totipotenz durchlaufen. Die Beiträge untersuchen, welche Konsequenzen sich aus dieser hypothetischen Annahme für die biologische Bedeutung und die moralische und rechtliche Bewertung von menschlichen Embryonen ergeben.Ausgehend von der Darstellung des historischen Konzepts und aktueller Begriffsbedeutungen von entwicklungsbiologischer Totipotenz wird im rechtswissenschaftlichen Teil untersucht, inwieweit Totipotenz ein adäquates oder ergänzungsbedürftiges Kriterium für die Legaldefinition des Embryos darstellt. Im Anschluss reflektiert der philosophische Teil den Embryobegriff unter den Aspekten der Potentialität, Natürlichkeit und Zweckbestimmungen. ····· 1036194114
für 70.00€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Die Anforderungen an die berufliche Pflege haben sich in den letzten Jahrzehnten grundlegend verändert.Um den Herausforderungen des demographischen Wandels sowie der epidemiologischen Entwicklung gerecht zu werden, hat sich die Pflege zu einer professionellen Dienstleistung weiterentwickelt, die größere Verantwortung in einem multidisziplinär vernetzten System der Gesundheitsversorgung beansprucht. Doch was macht gute, professionelle Pflege aus Welche Lehr- und Lernprozesse fördern die Entwicklung wichtiger Pflegekompetenzen Nadin Dütthorn vergleicht erstmals die Pflegeausbildung in Europa und zeigt eindrucksvoll, dass Pflegen und auch Lernen in der Pflege zum aktiv zu gestaltenden Beziehungserleben wird. ····· 1036194072
für 55.00€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Weltweit sind 130 bis 170 Millionen Frauen von weiblicher Genitalverstümmelung betroffen. Durch steigende Migration sind auch Länder wie Deutschland zunehmend mit diesem Problem konfrontiert. Dieser Band beleuchtet einerseits die Hintergründe der weiblichen Genitalverstümmelung und die ethische Komplexität der Praktik, andererseits wird eine Studie unter niedergelassenen Gynäkologen vorgestellt, um zu zeigen wie diese mit weiblicher Genitalverstümmelung umgehen, was ihr Kenntnisstand ist und wie sie die Problematik einschätzen. Der Band kann als Grundlage für eine reflektierte Auseinandersetzung mit weiblicher Genitalverstümmelung dienen, um sensible Maßnahmen gegen weibliche Genitalverstümmelung in Deutschland und weltweit zu ermöglichen. Betroffenen Frauen soll eine würdevolle Betreuung ermöglicht werden, die den kulturellen Hintergrund kennt und respektiert, jedoch gleichzeitig die Prävention von Genitalverstümmelung im Blick behält. ····· 1036193901
für 40.00€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Open Access - frei verfügbare elektronische Ausgabe Dieses Werk ist als Open Access-Publikation im Sinne der Creative Commons-Lizenz BY-NC-ND International 4.0 (`Namensnennung - Nicht kommerziell - Keine Bearbeitungen `) unter der DOI 10.14220/9783737000307 erschienen. Um eine Kopie dieser Lizenz zu sehen, besuchen Sie der größten Probleme bei der Prävention und Aufklärung von Foltervorfällen war lange Zeit das Fehlen allgemeingültiger Richtlinien zu deren Dokumentation. Erst 1999 wurden solche Standards unter dem Titel `Istanbul-Protokoll` veröffentlicht. Bereits ein Jahr später wurde das Dokument von der UNO angenommen. Der vorliegende Band bietet erstmals eine vollständige deutsche Übersetzung dieses `Handbuchs zur wirksamen Untersuchung und Dokumentation von Folter`. Er enthält Darstellungen der rechtlichen und ethischen Zusammenhänge sowie Hinweise zur Durchführung von Untersuchungen. Komplettiert wird er durch umfangreiche Erläuterungen zu den medizinischen - sowohl körperlichen als auch seelischen - Folgen von Folter. ····· 1036193880
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray A paired-like homeodomain transcription factor 2 (PITX2) is another new marker in breast carcinoma when hypermethylation at P2 promoter of this gene was noted to be associated with poor prognostic factor. We investigated the expression of PITX2 protein using immunohistochemistry in invasive ductal carcinoma and its association with the established growth receptors such as ER, PR and HER2. As conclusion,PITX2 is another potential prognostic marker in breast carcinoma that able to add significant information to established prognostic factors of ER and PR. The expression of PITX2 together with PR may carry a very good prognosis. ····· 1036192588
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray From man`s earliest attempts to manufacture tools and cloths and construct buildings, he has faced health risks from inhalable substances or dusts in the workplace. With sophistication of life and creation of villages, cities and societies, such risks became more serious. Fibrosis is the abnormal production of collagen fibers following tissue damage. This accounts for the formation of scar tissue. Lung fibrosis is one of the typical ways in which the lung reacts to damaging stimuli. Historically, idiopathic pulmonary fibrosis was thought to be a deleterious consequence of persistent lung inflammation that followed an unknown insult. It is clear that novel strategies are required in the treatment of pulmonary fibrosis. Specific anticytokine therapies will require evaluation, used either singly or in combination. In this book, we practically investigated the involving phenomena during the process of bleomycin-induced fibrosis in murine lung. ····· 1036192557
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Spinal and back deformities can lead to pain and discomfort, disrupting productivity, and may require prolonged treatment. The conventional method of assessing and monitoring the deformity using radiographs has known radiation hazards. An alternative approach for monitoring the deformity is to base the assessment on the shape of back surface. This publication presents the content and progression of research into automated analysis and visualization of three-dimensional laser scans of the human back. Using mathematical shape analysis, methods have been developed to detect the anatomic landmarks of the back from which the spinal mid-line is reconstructed and measurements of the deformity are derived. Effective visualization techniques which highlight asymmetry of the back have also been developed. ····· 1036192545
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Cigarette smoking is associated with an increase in risk of peptic ulcer and Gastro-Intestinal cancer. Oxidative and nitrosative stress accompanied by toxic materials in smoke and tar has a significant role in production of carcinogenic complexes and injury to DNA and cellular proliferation in gastric cancer. The study designed to compare the rate of injuri to DNA in gastric tissue, the levels of nitric oxide (NO0) and severity of oxidative stress in gastric juice of smoker and non-smoker patients with active peptic ulcer. Results of this study approve the direct relation between increase in DNA damage and toxic complexes existing in smoke and tar of cigarette, especially NOo radicals. It seems that reactive spaices of oxygen and nitrogene such as peroxide, peroxinitrit and new unknown complexes that forms mediating the reaction between tar and nitric oxide, have an important role in DNA damage and diseases related to tobacco products such as gastric cancer and results of this study based upon increase in superoxide dysmutase and gluthation peroxidase activities and reduction in total anti-oxidant capacity in gastric juice indicates the increase in oxidative stress in smoker`s gas. ····· 1036192497
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Natural compounds including flavonoids and alkaloids may play major role in scavenging free radicals, such as hydroxyl radical generated by chemotherapeutic in cells. Chemotherapy generates free radical damage DNA and induced genotoxic effects and event cell death there is possibility that pre treatment with flavonoids and alkaloids can induce protection against oxidative stress. The herbal extract selected for the present work contains a large number of flavonoids and alkaloids and other active compounds in a good concentration. ····· 1036192460
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Despite tremendous advances in the diagnosis and the management of oral cancers, this group of cancers is considered to be the one with the highest mortality as well morbidity rates with the diagnostic adjuncts which are used to aid an early diagnosis of oral cancers either suffering from a lack of sensitivity in the initial stages of the processes leading to frank oral cancers or suffering from a setback of not being so cost effective. In addition, biopsy, which is considered to be the gold standard in the diagnosis of oral cancers, suffers from the reliability of an appropriate site for the obtainment of the specimen to be conclusive depending largely on the area of the tumour sampled and the individual pathologist s criteria for evaluation. The introduction of the concept of the field of cancerization further questions the significance of biopsy results. The role of biochemical markers, on the other hand, comes out to be a convincing and early, enough evidence of the changes taking place in the body eventually turning out to develop into frank malignant degenerations. Hence, the present study was planned. ····· 1036192444
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Abnormalities during the life span of cell lead to serious fault and hence cell cannot function well and hence due to apoptosis the cell get suicide without harming the neighbor cell. Apoptosis is strictly regulated by cell machinery using Fas, Caspases, Death receptor and TNF receptors. Pancratistatin, alkaloids from the amaryllidaceae family induce the apoptosis in cancer cell by different mechanism like upregulation of Fas, increase in caspase-3, destabilization of mitochondrial membrane potential and flipping of phosphatidyl serine. Pancratistatin promises to induce the apoptosis in the cancer cells and produce lesser cytotoxic effect on the normal cells. This natural product can reveal and unveil the horizon for the new-targeted therapy, which is more effective and promising. Due to lesser yield of pancratistatin from the plant source, chemical synthesis by chemoenzymatic process is beneficiary to us for making library for the pancratistatin and its derivatives. ····· 1036192443
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Breast ultrasound is an adjunct to mammography and physical examination for breast masses by confirming diagnosis of cysts and providing accurate guidance for needle biopsy of vast majority of solid masses. In Sudan the incidence of cancer has been increased in the last years, this may be due to the risk factors (familial, hormonal, iatrogenic and radiation). Objectives of the study are to differentiate between cystic and solid masses, to observe criteria for differentiation between benign and malignant masses and also to increase the clinicians awareness regarding the important role of ultrasound guidance in interventional procedures safely. ····· 1036192436
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Low birth weight has been a cause of concern since times immemorial. But the identification of factors associated with it came only after many careful observations by many learned men and women at different times and places. Despite its Universal presence, it acquires significant importance in the developing countries of the world where social, demographic and environmental factors, almost always act as villains competing with the poor standards of healthcare in these countries. LBW is closely associated with fetal and perinatal mortality and morbidity, inhibited growth and cognitive development, and chronic diseases later in life. At the population level, the proportion of babies with a LBW is an indicator of a multifaceted public-health problem that includes long-term maternal malnutrition, ill health, hard work and poor health care in pregnancy. On an individual basis, LBW is an important predictor of newborn health and survival and is associated with higher risk of infant and childhood mortality. This study seeks to identify some of the factors associated with low birth weight seen in institutional deliveries at Katihar in a bid to explore the strategies for prevention. ····· 1036192380
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Majority of our healthcare provider working in Emergency Department has good knowledge, attitude & practice level in standard precaution. In fact, we found that (78.4%) were compliance to standard precaution practice. There were 43 participants who did not compliance to standard precaution practice, 14 were medical officer (32.6%), 14 were assistant medical officer (32.6%), 2 were staff nurses (4.7%), 3 were assistant nurse/community nurse (7.0%) and 10 were health attendants (23.3%). Most participants gave lack of time is the main reason for poor compliance with 38.5%, followed by interfering with their work with 29.2%, lack of equipment with 21.5% and other reason such as laziness, forgotten, not comfortable with standard precaution, lack of staff and very busy (10.8%). ····· 1036192282
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Microarray Data Analysis, Next Generation Sequencing Data Analysis, R package, Statistical data analysis, proteomics data analysis, RNA-sequence data analysis, SNP s and Haplotype mapping for genetic analysis, Copy Number Variation Detection, C, JAVA, Perl, SQL, Genome Analysis, Phylogenetic studies, Cluster analysis, Docking, BLAST, FASTA, CLUSTAL W&X, Database Management, Protein Modeling, Lead Identification & Optimization, Drug Designing. ····· 1036192216
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Hypernatremia is common among critically ill patients in ED and ICU. The physioLogiQ teaching highlights the hemeostasis derangements as a main factor of cellular dysfunction.Esspecially due to hypertonic hyperosmolality and cellular dehydration.Hypernatremia can be produced by either the administration of hypertonic sodium solutions or from loss of free water. In hospitalized patient, they become hypernatremic as a result of an inadequate fluid prescription or impaired thirst.Elderly patients also develop volume depletion because of sodium and water losses due to diuretics, vomiting, or diarrhea. Due to the importance of sodium in determining normal homeostasis which in turn will determine the recovery of the cellular dysfunction ,we conducted this study.The objective was to determine the correlation of hypernatremia with clinical outcome in critically ill patient. It is noted from the study that hypernatremia is associated with high mortality.This alarming findings has translated into the economics of health care affordability,length and duration of stay for critically ill patient. ····· 1036192197
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Nursing Medical Microbiology is the study of the causes and management of infectious diseases. These can be caused by viruses, bacteria, microfungi and protozoa. Nursing Medical Microbiology may overlap with parasitology, generally considered to be the study of diseases caused by multicellular parasites. Most of the microbes that live on or in humans do no harm. Indeed, they may be positively beneficial. The relationship is, however, finely balanced. Microbes are continually probing our defences and commensals that get into the `wrong` place can do untold damage. Peritonitis, for example is the life-threatening infection that results when gut microbes gain access to the peritoneal cavity, for example following a ruptured appendix. Urinary tract infections are most frequently caused when gut organisms or the skin flora gain access to the bladder. This is why, considering comparative anatomy, women are much more likely to suffer cystitis than men, for example. Some commensals can cause disease because of our life-styles. Dental decay in the Developed world is the result of metabolism of sugars in our diet by our oral flora to produce acid that subsequently etches our teeth. ····· 1036192095
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Due to the rising costs of health care in the US and the limited resources available for health prevention efforts, it is essential to organize and direct more effective efforts by public health officials and epidemiologists, as well as funding from local, state and federal governments, to reduce and eliminate identified health disparities. This study provides evidence of state-specific increases in oral cancer that are not associated with the increases previously observed among females and minorities, thereby providing new insights regarding potential methods to identify changes in relevant trends in geographic areas which may experience increases in tobacco-induced diseases in the future. As state and local public health professionals strive to formulate effective prevention and education programs for their residents, understanding the relationships between cause and effect, as well as the primary or secondary factors that more accurately indicate the potential for increased risk, becomes more imperative. ····· 1036192061
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Quetiapine, a dibenzothiazepine derivative, is a novel antipsychotic with demonstrated efficacy in acute schizophrenia. It is closest to Clozapine in its pharmacological profile but is free of the life threatening side effects like agranulocytosis. It may well replace Clozapine in the treatment of refractory schizophrenia and in bringing some miraculous improvements (awakening) in chronic schizophrenia. In addition to improvement in positive and negative symptoms it has also exhibited a beneficial effect for treatment of affective and cognitive dysfunctions in patients of schizophrenia. The salient feature of quetiapine is tolerability in terms of EPS, absence of any effect on prolactin levels and minimal effect on weight, that differentiate it from the other available antipsychotic drugs. Preliminary studies indicate that there is a high level of patient acceptability and satisfaction with quetiapine. Overall, quetiapine is as effective as risperidone or olanzapine for the treatment of psychotic symptoms, and is more effective for the treatment of depressive symptoms. It has an excellent risk/benefit profile and is a suitable first-line option for the treatment of schizophrenia. ····· 1036192000
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Cancer is a disease of uncontrolled cell growth and proliferation that is predicted to directly affect 1 in 3 Canadians. Standard chemotherapy that targets DNA or its replicative machinery effectively eradicates cancer cells, but also causes non-specific toxicity to healthy cells. Pancratistatin, a natural alkaloid isolated from Hymenocallis littoralis, was found to selectively induce apoptosis (programmed cell death) in many types of human cancer cells, with an insignificant effect on healthy non-cancerous cells. Major findings presented in this work are: the selectivity and efficacy of pancratistatin and synthetic derivatives on patient-obtained and commercially available leukemia the potent effect of pancratistatin on human colon and prostate cancer cells in vitro and in vivo and the unique mechanism of action of pancratistatin. In summary, pancratistatin is a natural anti-cancer compound that selectively targets cancer cell mitochondria to induce apoptosis and significantly reduces growth of human tumor xenografts. ····· 1036191964
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Successful periodontal therapy requires a proper and accurate diagnosis. Radiography is a valuable aid in the diagnosis of periodontal disease, determination of prognosis and evaluation of treatment outcome. However, the radiograph is an adjunct to clinical examination, not a substitute for it. The world of imaging for dentists has greatly widened in the past decade, no longer are we restricted to transmission radiography. Newer techniques have been developed that enhance our ability to see even small changes over time. The proper use and interpretation of these readily available diagnostic modalities requires a clear understanding of their respective limitations and capabilities. Clearly the end result of better diagnosis should be early intervention and better treatment. The present research focuses on, and attempts to present realistic, relevant, in detail review of current leading edge concepts, technologies and range of imaging techniques in radiology that have potential use for diagnosis of periodontal diseases and the application of this new knowledge to patient care. ····· 1036191945
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray 510 males with ischemic heart disease were asked to fill out the abridged five-item version of the International Index of Erectile Function (IIEF-5. 90.4% (461) of the respondents reported some degree of erectile dysfunction(IIEF-5 score 22). 24.5% have mild ED 26.7% have mild to moderate ED 5.5% have moderate ED and 33.7% have severe ED. Age above 60 years old and diuretic are the most significant risk factors for ED by logistic regression when adjusted for all confounding factors. Other important risk factors include diabetes and hypertension. Erectile dysfunction is common among patients with established coronary heart disease. In this study, the prevalence is much higher than that of the normal population.The prevalence and severity of ED increased significantly in men above the age of 50 years old. Diabetes, hypertension and diuretic use are important risk factors for erectile dysfunction. Understanding the magnitude of the problem and taking remedial steps may significantly improve the quality of life of these affected individuals. ····· 1036191894
····· lezzter Preis 71.10€ ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray This book was produced to answer the need expressed by Radiologists and trainee Radiology Technologists for clear and detailed description of the PACS and its uses in Radiology service. The concept of picture Archiving and Communication System (PACS) has now been in existence for over 20 years. Advances in computer hardware technology only enabled it to become a realistic clinical entity in the 1990s. PACS installations are now rising exponentially worldwide, and although most institutions with PACS have achieved a completely filmless working environment, few function in a paperless mode. PACS integrates imaging modalities, interfaces with hospital and departmental information systems, and manages the acquisition, storage, retrieval, and display of images to radiologists, hospital physicians, and remote referring physicians, specialists, clinics and imaging centers. PACS serves as a secure database for medical images, but more importantly, PACS improves the efficiency of imaging departments. ····· 1036191850· 1 · ::::: · 36 ·· 37 ·· 38 ·· 39 ·· 40 ·· 41 ·· 42 · ::::: · 74 ·
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