für 32.31€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Provedena otsenka kommunikatsionnoy effektivnosti proizvoditeley i distrib`yutorov farmatsevticheskogo rynka na urovne aptechnykh organizatsiy. Vyyavleny osnovnye nedostatki vo vremya provedeniya kampanii po prodvizheniyu. Takzhe izuchena rasprostranennost` osnovnykh sredstv i vidov prodvizheniya v aptechnykh organizatsiyakh vo vremya provedeniya issledovaniya. Opredeleno, chto prodvizhenie v aptekakh predstavleno vsemi osnovnymi sredstvami. ····· 1036118637
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The drugs incorporated in controlled release drug delivery systems shows variations in bioavailability due to their selective absorption from specific part of stomach and upper gastro-intestinal tract. In this book, various gastro-retentive approaches have been described for increasing therapeutic performance of drugs having absorption potential from stomach. A major focus has been given on the hydrodyanamically balanced systems, its formulation aspects and effects of excipients and processing parameters. The various types of gastro-retentive drug delivery systems have been well illustrated with diagrammatic illustrations wherever necessary. Also major attention has been given on evaluation of these drug delivery systems. The currently available gastro-retentive drug delivery systems in market have been described. The future potentials of these drug delivery systems have been presented. This book will be useful for the students at graduate level, post graduate students and research scholars for understanding the basics of gastro-retentive drug delivery systems. ····· 1036118618
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray A simple, sensitive and validated HPLC method has been developed to determine esomeprazole and domperidone in tablet dosage form. The chromatographic separation was achieved on a hyperchrome C-18 column column (4.6 x 150mm, 5 particle size) analytical column using a mixture of acetonitrile: Phosphate buffer (pH 5.0) in the ratio of 60:40 (v/v) used as the mobile phase, at a flow rate of 1.0 ml/min and detector wavelength at 290 nm. The validation of the proposed method was carried out for specificity, linearity, accuracy, precision, limit of detection, limit of quantitation and robustness. Linearity of method was found to be in concentration range 10-50 g/ml for esomeprazole and 5-25 g/ml for domperidone with correlation coefficient greater than 0.9999. The retention time of domperidone and esomeprazole was found to be 2.92 and 3.91 min respectively. The method can be used for simultaneous determination of esomeprazole and domperidone. ····· 1036118603
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray A successful attempt was made for the spectrophotometric quantitative estimation of two antihypertensive marketed combinations using mixed hydrotropic agent. The method was developed by experimentation based on thorough literature survey and ascertained by statistical parameters of sampling. The entire work was performed on Shimadzu UV/VIS double beam-double detector spectrophotometer (Model-1700 series). The result obtained shows the developed method to be precise, simple, rapid and accurate. Thus these can be used for routine analysis of Eprosartan, Hydrochlorothiazide, and Olmesartan Medoxomil in bulk drug and tablet dosage form instead of processing of extraction using organic solvent separately. It may reduce the large total concentration of hydrotropic agents necessary to produce modest increase in solubility by employing combination of agents in lower concentration. Spectrophotometric precluding the use of organic solvents and thus avoids the problem of residual toxicity, error due to volatility, pollution, cost etc. ····· 1036118475
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Development of a pharmaceutical product is essentially a technique where in physicochemical properties of an active ingredients, excipients and manufacturing process are manipulated to achieve desired qualities in pharmaceutical finished dosage form. Certain goals such as product specifications, ease of manufacturing cost etc are defined for a dosage form prior to initiating the development work. The traditional trial and error approach may be less dependable and more time consuming and often provides an approximately or marginally acceptable formulation and process. In today s market optimization requires skill in understanding physicochemical properties of their materials and effect on the process identification and independent (cause) and dependent(effective) variables and understanding of expected relationship between cause and effect is crucial to the success of this approach. ····· 1036118471
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Mycobacterium tuberculosis (MTB), the pathogenic agent of tuberculosis (TB), is responsible for the death of 2 3 million people annually and for a global economic toll of $12 billion each year. Thus, there is an urgent need to develop new therapeutics for tuberculosis, to reduce the duration of treatment and to provide a more effective therapy for MDR TB and for latent tuberculosis infection. In the present investigation, a series of 4-(4-(dimethylamino) benzyl)-3-methyl-1H-pyrazol-5(4H)-one analogues of pyrazole were synthesized by cyclization of mannich base with hydrazine hydrate. The nitrogen functionality of 4-(4-(dimethylamino) benzyl)-3-methyl-1H-pyrazol-5(4H)-one was alkylated with different halogenated alkylated substituted chain in the presence of base. The chemical structure of compounds were proved by IR, MASS, 1HNMR spectroscopy data and elemental analysis. . The antitubercular activity of these compounds were evaluated by microdilution method against M. Tuberculosis H37Rv micobactrium strain of M. Tuberculosis compared with standard INH, RIF & ETM. ····· 1036118453
für 35.91€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Autoimmunity is physiological condition with uncontrolled and excessive production of antibodies. Such uncontrolled production of antibodies are the result of excessive release of chemical mediators of inflammation specially cytokines. The autoantibody plays a sinister and pivotal role to induce several autoimmune diseases which make one`s life difficult and arduous. Present work is an attempt to underline the role of cytokine to show their negative importance. Furthermore, the book provides safe immune depressant plant drugs which might help either to treat or to stop the progress of such untreatable disease. ····· 1036118428
für 49.41€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Most of herbal formulations have lacking of preformulational and post formulational studies. Thus, an attempt was made to performed the preformulation and post formulation characteristics for senna leaf powder and calcium sennoside. The conventional tablet of senna leaf powder and calcium sennoside may release a significant amount of drug in the physiological environment of stomach before reaching at the site of action. Hence, enteric coated tablet of calcium sennoside and senna leaf powder was prepared using cellulose acetate phthalate for averting the initial loss of 5-8% sennoside in stomach. For this purpose different formulational factors were optimized. The in-vitro release of coated tablet was performed in 0.1 N Hcl and phosphate buffer of pH 6.8. After the enteric coating, the tablet ensured that it was more pH dependent and release the drug only at higher pH. This research work should be especially useful to professionals engaged in formulation development of herbal drugs, or anyone else who wants to perform the preformulation and post formulation study of herbal drugs. ····· 1036118425
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray To evaluate the Analgesic, Antipyretic and Antiarthritic activities of leaves extract of Tridax procumbens Linn. (Ethanolic and ethyl acetate) Analgesic activity was investigated against Acetic acid and sodium chloride induced Writhing test in rats. TPEE at 300mg/kg (P.O.) shows better analgesic activity than TPEAE. Ethanolic and Ethyl acetate extracts of Tridax procumbens were evaluated for antipyretic activity using hyperpyrexia induced in rabbits by Typhoid-Paratyphoid A, B vaccine. Like Paracetamol 100 mg/kg (I.V.) Tridax procumbens showed significant reduction in elevated body temperature at 300 mg/kg (P.O.) while Antiarthritic activity of Tridax procumbens leaves extract in complete Freud s adjuvant induced arthritis in rats. Antiarthritic activity was assessed based on the Physiological parameters, Haematological parameters and Knee joint Histopathology. The changes in the above said parameters were reversed by the Tridax procumbens leaves extract administered at the dose of 300 mg/kg orally. Hence further detailed investigation is required to isolate the compound responsible for the evaluated activities. ····· 1036118411
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Dipeptidyl Peptidase-IV (DPP-IV) was found to be one of the emerging targets in the field of antidiabetic drug development. In recent years, Piperidone analogs have shown their application in the field of diabetology as observed in the crystallographic structure of DPP-IV. All the ligand molecules were designed considering the pharmacophoric features of the GGO901 (Co-crystallised ligand of DPP-IV with the PDB entry-2OQI). It was thought worthwhile to perform docking study by extracting the crystallographic structure of Dipeptidyl Peptidase-IV inhibitor with all the virtually developed molecules to ensure the better binding energy which would be well able to explain the ligand target interaction of novel piperidone analogs, actively inhibiting DPP-IV enzyme. Based on the docking output, a few novel imidazole linked piperidone analogs were synthesized & as a part of the structure elucidation process various spectroscopic data were collected and subsequently analysed. All the analytically proven synthesized compounds were further sent for biological evaluation. ····· 1036118368
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Lantana camara L. is regarded both as a notorious weed and a popular ornamental garden plant and posseses various uses in folk medicine in many parts of the world. The phytochemical investigation of the methanolic extract of leaves resulted in isolation terpenoidal glycosides namely urosolic acid glycosidic oleiate (NEW), ursolic acid glycosidic stearate (NEW) and oleanolic acid glucoside. Some esters like undecanyl Oleioate, dodecanyl oleioate and carboxylic acids like ursolic acid and oleanolic acid were successfully isolated. HPTLC fingerprint of the methanolic extracts of L. camara leaves were performed. The solvent systems were chloroform: methanol (99:1). Antidiabetic activities of the Lantana camara were performed on streptozotocin induced diabetic rats and the aqueous extracts of both the drugs showed significant reduction in blood glucose level. ····· 1036118357
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The present studies were carried out to observe the effects of mother tinctures of two homeopathic medicines, that is Momoradica charantia and Syzygeum jambolanum. Twenty patients of type 2 (18 males and 2 females) with mean age of 40 years were included in the clinic trials of M. charantia. And twenty patients of types-2 (17 males and 3 females) with mean age of 40 years were included in the clinic trials of S. jambolanum. The blood samples were collected at zero day before the start of trial and after 7, 14, and 21 days of medication. Blood sugar levels were monitored as a function of anti-diabetic effects of these drugs. The results reveal that Momoradica charantia (Karela) no antidiabetic effect and it is the Syzygeum jambolanum (Jamen) which has strong effect where in blood sugar level decreases from 175±3 (mean± sem) mg/dl at zero day to 112±mg/dl at 21 day. ····· 1036118308
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray UPLC - Ultra performance Liquid Chromatography, is highly sophisticated advanced instrument introduced in the Pharma Industries. Here we have covered the advancements that have been made in this instrument by giving more stress on its columns. It comprises of five types of columns each designed for specific samples. This book also covers the specification of the columns, along with their instrumentation. ····· 1036118259
für 61.20€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Pharmacognostical and Pharmacognostical Screening of the Medicinal Plant Plumeria Alba Linn. (Apocynaceae) in Cancer Therapy, is used in the treatment of ulcers, herpes, scabies and seeds possess haemostatic. The bark is bruised as plaster over hard tumours. Only a very limited research has been carried out on the plant, under the present study assumes singular significance and it is supposed to contribute a great deal to the existing literature. It highlights the macroscopic and microscopic characters of leaf, petiole, physic chemical evaluation and preliminary photochemical studies of the plant. This research concluded that this plant possess significant anticancer activity after applying in vivo and invitro models. ····· 1036118223
für 71.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Quality may appear to be a nebulous term. The U.S. Office of Technology Assessment has defined the quality of medical care as evaluation of the performance of medical providers according to the degree to which the process of care increases the probability of outcomes desired by patients and reduces the probability of undesired outcomes, given the state of medical knowledge . The Institute of Medicine (IOM), in a report entitled, Medicare: A Strategy for Quality Assurance, stated that quality of care is the degree to which health services for individuals and populations increase the likelihood of desired health outcomes and are consistent with current professional knowledge , whereas Ovretveit (1992) simply states, A quality health service/system gives patients what they want and need. All of these definitions may provide the best explanation of the concept of quality in health care. Each provides additional insight into quality, what we can expect from quality, and how quality can be perceived. Pharmacy service quality has been measured by assessing its structure, process, and outcomes. ····· 1036118212
für 35.91€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Herbal formulations are becoming integral part of health care system for both preventative and therapeutic purposes around the globe. There is a continuous increase in demand of this product in the international market. With increasing number of people switching once again towards the traditional system of medicine, it is important that they receive authentic medicines. Polyherbal oils are therapeutically active oils either obtained in pure form from various sources or prepared by digestion of herbs and minerals in suitable oil base. Polyherbal oils are popular means of treatment for various ailments, specially pain and skin diseases. Standardization of medicinal oils in terms of composition is important to ensure optimum levels of active principles for their bio-potency. Modern chromatographic methods are most widely used for marker based standardization. In the last two decades HPTLC and HPLC have emerged as an efficient tool for the phytochemical evaluation of herbal drugs. Present book is an attempt to provide guidance on development and validation of HPTLC and HPLC methods for marker based quantitation of polyherbal oils. ····· 1036118132
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Phytochemical markers are pivotal in the current practice of quality control since they are used as indicator at various stages of development and manufacturing of herbal medicine. Recent approaches of applying hyphenated chromatography and spectroscopy such as HPLC, LCMS and HPLC-NMR could provide the additional spectral information, which will be very helpful for the qualitative analysis and structural elucidation. A chemical fingerprint obtained by hyphenated chromatography, can become the primary tool for quality control of herbal medicines This book provides detailed pharmacognostic and phytochemical study, isolation, purification, analytical method development of Swertiamarin, Isoswertisin-5-O- -D-glucoside, Quercetin, Swertisin and safety, antidiabetic activity of ethyl acetate extract of Enicostemma littorale. ····· 1036118069
für 44.91€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Aujourd`hui, la pharmacie est représentée par 22279 points de vente (données de l`ordre national des pharmaciens, Septembre 2015) et 4 millions de clients potentiels journaliers. Ce circuit de distribution, très bien organisé, est en pleine mutation (déficit de la sécurité sociale, auto-médication, déremboursements des médicaments...). Cependant, le secteur des dermocosmétiques, est quant à lui en forte croissance. Les enjeux de demain pour les pharmacies sont donc multiples et vont nécessiter une restructuration progressive des officines. L`objectif de cette thèse est de donner aux pharmaciens les clés pour développer leur espace hygiène-beauté dans le but de se différencier de la concurrence et d`augmenter leurs parts de marché. Ils pourront ainsi utiliser les recommandations proposées et les intégrer à d`éventuels futurs programmes de formation des équipes officinales. ····· 103614752
····· lezzter Preis 44.10€ ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The essence of pharmaceutical formulations such as tablets gets defeated due to problems with disintegration, dissolution and consequently absorption. Bioavailability of solid dosage forms plays a crucial role in formulations and usually calls the attention of drug regulators. This book seeks to bring to the fore a scientific investigation into the dissolution and implicitly the efficacies of certain brands of albendazole tablets (anthelmintic) on the Ghanaian market. ····· 103613844
für 55.71€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Fast Dissolving Tablets of Thiabendazole is designed for Providing the better and effective treatment against Helminthiasis. Fast Dissolving Tablet of Thiabendazole is designed with the aim to enhance the bioavailability of the dosage form. Helminthiasis infection is very common in urban areas and particularly in the childrens that are playing in soil so the Fast dissolving tablet of Thiabendazole provide cidal action by inhibiting the enzyme fumarate reductase so it provide a safest action and effective treatment. ····· 103613736
für 35.91€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Vaccination is a cost effective means of disease prevention that has already prevented millions of people from death. Recent advances have led to the development of new and promising vaccine strategies, which include development of polysaccharide, subunit/ recombinant vaccines. These vaccines have better safety profile but poor immunogenecity, which require immunopotentiators as adjuvants. Currently many immunomodulators including biological, synthetic and naturals are under evaluation as safer and effective immuno-adjuvants. Hence it requires safer and effective vaccine adjuvants. Botanical immunomodulators are under evaluation as newer and safer adjuvants. Withania somnifera (WS) is a immunomodulator from natural sources which is also mentioned in Rasayana. This present study is an attempt to evualate Immunoadjuvant activity of WS in an experimental system using DPT vaccine and flow cytometry. The results suggests modulatory effect of WS on CD4 and CD8 percentages resulting in significantly higher anti-diptheria antibody titres coupled with protection even with lower imuunogenic doses of DPT vaccine. ····· 103613674
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The aim of present study was to assess the anti-inflammatory activity of polyherbal formulation of leaves of Annona squamosa, Azadiracta indica and rhizome of Curcuma longa. The mature green leaves of Annona squamosa, Azadiracta indica and rhizome of Curcuma longa were collected and authenticated. Extractions of dried leaves and rhizome were carried out with ethanol in soxhlet apparatus. The polyherbal formulation showed the significant anti-inflammatory activity comparable to the standard drug Diclofenac sodium against carrageenan induced rat paw edema method. The polyherbal formulation reduced the inflammation induced by carrageenan by 44.60% and 62.43% on oral administration at 100 mg/ kg and 200 mg/kg respectively as compared to the control treated group. ····· 103613584
für 44.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray The hydro-alcoholic extract of Boerhaavia diffusa of leaves was investigated for evaluation of exhibited anxiolytic activity in rats at a dose 100 and 200 mg/kg by p.o. route for Elevated Plus Maze test, Hole Board Test, Haloperidol Induced Catalepsy and Ketamine induced Sleep method.. Results of in-vivo activity lead to the conclusion that the hydro-alcoholic of Boerhaavia diffusa showed predominantly significant activity which is compared to the standard drug Diazepam (0.5mg/kg). ····· 103613230
für 53.10€ kaufen ···· Rheinberg-Buch.de - Bücher, eBooks, DVD & Blu-ray Today, there are very old traditions and records of popular healing methods that have maintained their importance despite new developments and progress in the field of Chemistry, Pharmacy and Medicine. Indeed interest in herbal drugs is increasing. The curative parts of herbal drugs are not simply its woody stem or its leaves but the number of chemical compounds (phytoconstituents) it produces and uses for its own growth like flavonoids, alkaloids, mucilage, protein, carbohydrate etc. The genus Vitex has been carefully studied for its phytoconstituents as well as biological activities. Out of 250 species of this genus distributed all around the world, only 28 species have been phytochemically examined. Vitex species are already in use in herbal formulation. Hence exploration of this species both phytochemically & biologically, is by no means exhaustive & there still remains more scope for the study of bioactive molecules. Hence in current studies the plant Vitex leucoxylon has been selected for there pharmacological and phytochemical study. The detailed study of Vitex leucoxylon is included in this book and various important findings of the plant are included in this research book. ····· 103613218· 1 · ::::: · 20 ·· 21 ·· 22 ·· 23 ·· 24 ·· 25 ·· 26 · ::::: · 27 ·
Affiliate Marketing
AdHoc MeldungenAffiliate & PublisherAdvertiser & MerchantAcademyAntwortenArtikelsucheAdventskalender
AffilitivProduktdatenPreisvergleich
